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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Typical usage: Lower respiratory tract infections, ENT infections, and genitourinary infections.
Side Effects: Diarrhea, abdominal pain, loose bowel movement, nausea, and rash.
Drug Interaction: Faropenem is known to interact with other drugs like imipenem, cilastatin, furosemide, sodium valporate. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism Of Action: Faropenem interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPĚs are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Eventually faropenem binds to PBP and leads to cell lysis and death.
No substitutes found