Select to order medicines [Delhi/ NCR/ Bangalore/Mumbai]
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Typical usage: Hypertension. Angina pectoris. Migraine. Oesophageal spasm. Uterine relaxant (if used early).
Side Effects: Flushing, dizziness, exacerbated angina, bradycardia, hypotension, unconsciousness, headache, palpitation, GI upset, ankle swelling, paresthesias.
Drug Interaction: Nifedipine is known to interact with other drugs like atenolol, bisoprolol (Fumarate), cimetidine (HCl), clonidine (HCl), diazoxide, digoxin, fluoxetine (HCl), fosinopril (Na), fosphenytoin, human insulin, insulin lispro, magnesium sulphate. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism Of Action: It is a calcium-channel blocker; inhibits transmembrane influx of extracellular calcium ions across myocardial and vascular smooth muscle cell membranes without changing serum calcium concentrations; this results in inhibition of cardiac and vascular smooth muscle contraction, thereby dilating main coronary and systemic arteries
Showing 5 of 7
Showing 5 of 7