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Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Typical usage: Disorders of calcium balance, Edema, Heart failure, Hypertension, Oedema, and can also be given in adjunctive therapy as an alternative drug of choice in Diabetes insipidus.
Side Effects: Dizziness, Thirst, Headache, Nausea, Gout, Impotence, Polyuria, Night cramps.
Drug Interaction: None mentioned.
Mechanism Of Action: Hydrochlorothiazide, a thiazide diuretic, inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5% of total sodium reabsorption.
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Hypertension.
Side Effects: Nausea, stomach upset, skin rash, acute toxicity.
Drug Interaction: Potassium Sparing Water Tablets (Diuretics) Potassium Supplements Potassium-Containing Salt Substitutes Lithium.
Mechanism Of Action: Telmisartan is used to reduce high blood pressure. It is an angiotensin-II receptor antagonist, sometimes known as an antihypertensive. It is used to treat high blood pressure (hypertension). Angiotensin II is produced in your body and causes your blood vessels to narrow, increasing your blood pressure. Telmisartan blocks the effects of angiotensin II, so that your blood vessels relax and your blood pressure is lowered. Telmisartan is also used in the prevention of cardiovascular events such as heart attacks and strokes in patients who are at risk because they have reduced or blocked blood supply to the heart or legs or have had a stroke or have high risk type 2 diabetes. In general this drug is used for high blood pressure (hypertension). Benefits of being on this drug can include a reduction in blood pressure which is associated with a reduction in the risk of stroke, heart attack, heart failure, blindness or kidney failure.
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Showing 5 of 18