Zenflox Plus (200mg)

(10 Tablets in Strip)
-10+
Tablet
(1 Strip)
Rs. 9 / Tablet
Rs.90

SALT INFORMATION

Cefixime(200MG)

INDICATORS

Pregnancy:B Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

Infections of respiratory, urinary and biliary tract. Salmonella infection.

SIDE EFFECTS

Pseudomembranous colitis, thrombocytopenia, thrombophlebitis, leucopenia, seizures, flatulence, dizziness, headache, nausea, vomiting, anorexia, diarrhea, abdominal pain, urticaria, pruritus, dyspepsia, hypersensitivity.

DRUG INTERACTION

Probenecid may increase the blood concentration of cefixime by decreasing removal of cefixime by the kidney. May increase prothrombin time with anticoagulants.

MECHANISM OF ACTION

Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefixime interferes with an autolysin inhibitor.

Ofloxacin(200MG)

INDICATORS

Pregnancy:C Lactation:L5 Lab:NA Food:NA

TYPICAL USAGE

Genito urinary, respiratory, gastro intestinal. skin and soft tissue infections. Peritonitis, Gonorrhoea. Typhoid fever, Multi drug resistant tuberculosis. Acute and sub-acute eye and ear infections.

SIDE EFFECTS

Sinus tachycardia, hallucinations, stevens johnson syndrome, seizures, tendon rupture, dizziness, headache, nausea, vomiting, diarrhea, insomnia, abdominal pain, pruritus, photosensitivity.

DRUG INTERACTION

Ofloxacin is known to interact with other drugs like aluminium hydroxide and oxide, didanosine, iron Salts, pentostatin, probenecid, procainamide (HCl), sucralfate, theophylline. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Ofloxacin acts on DNA gyrase and toposiomerase IV, enzymes which, like human topoisomerase, prevents the excessive supercoiling of DNA during replication or transcription. By inhibiting their function, the drug thereby inhibits normal cell division.

SUBSTITUTES

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