CompositionOmega-3 Fatty Acids(2)
SALT INFORMATIONOmega-3 Fatty Acids(2)
INDICATORSPregnancy:NA Lactation:NA Lab:NA Food:NA
Used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe ( > 500 mg/dL) hypertriglyceridemia.
Eructation, dyspepsia, taste perversion.
Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval.
MECHANISM OF ACTION
Omega-3-fatty acids causes inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase, increased mitochondrial and peroxisomal P-oxidation in the liver, decreased lipogenesis in the liver, and increased plasma lipoprotein lipase activity and reduce the synthesis of triglycerides (TG) in the liver because EPA and DHA are poor substrates for the enzymes responsible for TG synthesis, and EPA and DHA inhibit esterification of other fatty acids.
- No substitutes found