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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Partial onset seizures. Myoclonic seizures, Primary generalized tonic-clonic seizures.
Side Effects: Dizziness, vertigo, headache, drowsiness, ataxia, anorexia, nervousness, rashes, depression, tremor, asthenia, aggression.
Drug Interaction: Levetiracetam is known to interact with other drugs like carbamazepine, triprolidine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism Of Action: The exact mechanism of action is unknown but does not involve inhibitory and excitatory neurotransmission. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hypersynchronization of epileptiform burst firing and propagation of seizure activity.
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