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There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Schizophrenia. Acute mixed or manic episodes in bipolar disorder.
Side Effects: Nausea, stomach upset, skin rash, acute toxicity.
Drug Interaction: Carbamazepine (Tegretol) can reduce blood concentrations of olanzapine, possibly necessitating higher doses of olanzapine. Other drugs that may also reduce blood levels of olanzapine areomeprazole (Prilosec) and rifampin. Smoking may reduce blood concentrations of olanzapine. Ciprofloxacin (Cipro), diltiazem (Cardizem, Dilacor, Tiazac), erythromycin, and fluvoxamine (Luvox) may have the opposite effect, that is, they may increase blood levels of olanzapine, and the dose of olanzapine may need to be reduced. Olanzapine can causeorthostatic hypotension, a drop in blood pressure upon standing up that may cause dizziness or even fainting. Taking olanzapine with eitherdiazepam (Valium), other related benzodiazepines or alcohol can exaggerate the orthostatic hypotension caused by olanzapine.
Mechanism Of Action: This medication is an antipsychotic agent, prescribed for depression, and psychoses.
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Showing 5 of 95