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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Duodenal and gastric ulcers, reflux or ulcerative oesophagitis. Zollinger-Ellison syndrome. NSAID-induced ulcers.
Side Effects: Renal failure, interstitial nephritis, fulminant hepatic failure, tachycardia, drowsiness, headache, flatulence, dizziness, headache, fatigue, nausea, diarrhea, myalgia, constipation, insomnia, abdominal pain, dry mouth, urticaria, pruritus, photosensitivity, skin rash.
Drug Interaction: Omeprazole is known to interact with other drugs like alprazolam, clarithromycin, clobazam, cyanocobalamin, diazepam, digoxin, escitalopram, lansoprazole, methotrexate, phenytoin (Na), riluzole, sodium diatrizoate, theophylline, toclizumab, warfarin (Na). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism Of Action: Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By acting specifically on the proton pump, omeprazole blocks the final step in acid production, thus reducing gastric acidity.
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Showing 15 of 529