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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Angina, Anxiety tachycardia, Arrhythmias, Cardiac arrhythmia, Hypertension, Hypertrophic obstructive cardiomyopathy, Induction and maintenance of anaesthesia, Induction of general anaesthesia, Iron deficiency anaemia, Migraine, Migraine prophylaxis, Obstructive cardiomyopathy, Reduction of raised intracranial pressure, Renal hypertension.
Side Effects: Fatigue, Nausea, Diarrhea, Cold extremities, Constipation, Insomnia, Impotence, Vivid dreams, Lassitude.
Drug Interaction: Decreased effect with aluminum and calcium salts.
Mechanism Of Action: Propranolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension.
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Showing 5 of 24