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There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Reversible airways obstruction, premature labour.
Side Effects: Fine skeletal muscle tremor especially hands, tachycardia, palpitations, muscle cramps, headache, paradoxical bronchospasm, angioedema, urticaria, hypotension and collapse.
Drug Interaction: Reversible airways obstruction, premature labour.
Mechanism Of Action: Salbutamol is a direct-acting sympathomimetic with ?-adrenergic activity and selective action on ?2 receptors, producing bronchodilating effects. It also decreases uterine contractility.