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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
There is positive evidence of risk to a breastfed infant or to breastmilk production, but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant (e.g. if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).
Side Effects: Nausea, stomach upset, skin rash, acute toxicity.
Drug Interaction: No drug interactions have been described with Tobramycin eye drops or ointment.
Mechanism Of Action: Sodium cromoglicate works by reducing allergic responses. It is not fully understood how it does this, but it is thought to work by 'stabilising' immune cells called mast cells.