Select to order medicines [Delhi/NCR /Bangalore /Chennai /Bhubaneswar /Mumbai]
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Drug which has been studied in a limited number of breastfeeding women without an increase in adverse effects in the infant; And/or, the evidence of a demonstrated risk which is likely to follow use of this medication in a breastfeeding woman is remote.
Typical usage: Depressive illness accompanied by anxiety, agitation, restlessness and disturbances of sleep. Masked depression, dysphoria and depression in alcoholics.
Side Effects: Postural hypotension, tachycardia, cardiac arrhythmias, conduction disturbances, congestive heart failure, hypotension, cardiac arrhythmias, coma, seizures, blurred vision, dry mouth, urinary retention, hypothermia, metabolic acidosis, mydriasis, weakness, dizziness, headache, fatigue, constipation, dry mouth, blurred vision.
Drug Interaction: Amitriptyline is known to interact with other drugs like adrenaline, alcohol, antazoline, apraclonidine (HCl), astemizole, bethanidine (Sulphate), bretylium (Tosylate), carbamazepine, cimetidine (HCl), cisapride, clonidine (HCl), debrisoquine (Sulphate), disopyramide, disulfiram, enflurane, ergotamine (Tartrate).
Mechanism Of Action: Amitriptyline is a TCA that exerts its action by blocking neuronal re-uptake of noradrenaline and serotonin thus increasing synaptic concentration of serotonin and/or norepinephrine in the CNS.
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Showing 5 of 47