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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
There are no controlled studies in breastfeeding women, however the risk of untoward effects to a breastfed infant is possible; or, controlled studies show only minimal non-threatening adverse effects. Drugs should be given only if the potential benefit justifies the potential risk to the infant.
Typical usage: Improve blood flow to labyrinth and brain stem. Vertigo, tinnitus, Meniere disease, loss of memory, motion sickness, cerebrovascular and peripheral vascular
Side Effects: Tardive dyskinesia, parkinsonism, extrapyramidal symptoms, headache, drowsiness, GI upset, unsteadiness.
Drug Interaction: Cinnarizine is known to interact with other drugs like Domperidone. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism Of Action: Cinnarizine inhibits contractions of vascular smooth muscle cells by blocking L-type and T-type voltage gated calcium channels. Cinnarizine has also been implicated in binding to dopamine D2 receptors, histamine H1 receptors, and muscarinic acetylcholine receptors.
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Showing 5 of 46