Sudopen (500 Mg)
SALT INFORMATIONDoripenem(500 mg)
INDICATORSPregnancy:B Lactation:L3 Lab:NA Food:NA
Complicated intra-abdominal infections, complicated urinary tract infections, pyelonephritis, nosocomial pneumonia.
Headache, nausea, diarrhoea, rash, phlebitis, elevated hepatic enzymes, oral candidiasis, anaemia, vulvomycotic infection, renal impairment, neutropenia, leucopenia, thrombocytopenia.
Doripenem is known to interact with other drugs like valproic acid, probenecid. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Doripenem is a broad-spectrum carbapenem with potent in vitro antibacterial activity against aerobic and anaerobic gram-positive and gram-negative bacteria including Pseudomonas aeruginosa. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins; which in turn inhibits the final transpeptidase step of peptidoglycan synthesis in bacterial cell walls.
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