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Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: Treatment of depressive illness in the initial phase and as maintenance against potential relapse/recurrence. Treatment of panic disorder with or without agarophobia.
Side Effects: Bradycardia, convulsions, respiratory depression, respiratory depression, hypoxia, dizziness, headache, nausea, vomiting, insomnia, dry mouth, sedation.
Drug Interaction: Citalopram is known to interact with other drugs like alcohol, cimetidine (HCl), iproniazid phosphate, methotrimeprazine (Maleate), methylamphetamine, naratriptan.
Mechanism Of Action: Citalopram blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT1A autoreceptors. SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs.
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Showing 5 of 27