Fibator Ez

(10 Tablets in Strip)
-10+
Tablet
(1 Strip)
Rs. 15.20 / Tablet
Rs.152

SALT INFORMATION

Atorvastatin(10mg)

INDICATORS

Pregnancy:X Lactation:L5 Lab:NA Food:NA

TYPICAL USAGE

Primary hypercholesterolaemia, heterozygous familial hypercholesterolaemia, homozygous familial hypercholesterolaemia or combined hyperlipidaemia.

SIDE EFFECTS

Flatulence, diarrhoea, nausea, vomiting, anorexia, xerostomia, angioedema, myalgia, rash, pruritus, alopecia, allergy, infection, chest pain.

DRUG INTERACTION

Atorvastatin is known to interact with other drugs like alvimopan, atazanavir, boceprevir, carbamazepine, clarithromycin, cyclosporine, dronedarone, erythromycin, etravirine, ketoconazole, nefazodone. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in the cholesterol biosynthesis pathway, this results in a subsequent decrease in hepatic cholesterol levels. Decreased hepatic cholesterol levels stimulates upregulation of hepatic LDL-C receptors which increases hepatic uptake of LDL-C and reduces serum LDL-C concentrations.

Ezetimibe(10mg)

INDICATORS

Pregnancy:C Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

Hypercholesterolaemia.

SIDE EFFECTS

Pancreatitis, muscular weakness, chest pain, dizziness, headache, diarrhea, cough, mild stomach pain.

DRUG INTERACTION

Ezetimibe is known to interact with other drugs like sitosterol. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Ezetimibe localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol. This leads to a decrease in the delivery of intestinal cholesterol to the liver.

Fenofibrate(160mg)

INDICATORS

Pregnancy:C Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

Hypercholesterolaemia, hyperlipoproteinaemia, prophylaxis of NSAID-associated gastric or duodenal ulcer.

SIDE EFFECTS

Hepatitis, rhabdomyolysis, headache, diarrhea, myalgia, constipation, skin rashes, impotence, decrease in libido.

DRUG INTERACTION

Fenofibrate is known to interact with other drugs like Acenocoumarol, Anisindione, Cerivastatin, Dicumarol, Lovastatin, Pravastatin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Fenofibrate exerts its therapeutic effects through activation of peroxisome proliferator activated receptor a (PPARa). This increases lipolysis and elimination of triglyceride-rich particles from plasma by activating lipoprotein lipase and reducing production of apoprotein C-III.

SUBSTITUTES

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