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Istamet (50/500 Mg)

(10 Tablets in a Strip)
Rs 308.0   per Strip Now Rs 308.0 YOU SAVE 0.0 %
14 Tablet  (1 Strip) Enter Pincode

Composition

SALTS:    Metformin (500MG) | Sitagliptin (50MG)

Salt Information

Metformin

Pregnancy: X Lactation: L5 Lab: NA Food: NA

Typical usage: Diabetes mellitus, Hyperlipoproteinaemia, Insulin dependent diabetes mellitus, Insulin resistance, Non-insulin dependent diabetes mellitus, Obesity.

Side Effects: Vasculitis, Pneumonitis, Malabsorption of vit B12, Malabsorpton of folic acid, Megaloblastic anemia, Hypoglycemia.

Drug Interaction: Additive effect with sulphonylureas. Glycaemic control may be affected by diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens.

Mechanism Of Action: The exact mechanism of action of metformin is unclear but it appears to reduce glucose absorption from the GI tract, reduce gluconeogenesis and enhance insulin sensitivity by increasing peripheral glucose uptake and utilisation.

Sitagliptin

Pregnancy: B Lactation: L5 Lab: NA Food: NA

Typical usage: Type II Diabetis Mellitus.

Side Effects: Headache, diarrhoea, upper respiratory tract infection, nasopharyngitis.

Mechanism Of Action: Sitagliptin inhibits dipeptidyl peptidase IV (DPP-IV), resulting in prolonged active incretin levels. Incretin hormones increases insulin synthesis and release from pancreatic ?-cells and reduces glucagon secretion from pancreatic ?-cells. Reduced glucagon secretion leads to decreased hepatic glucose production.

Substitutes

Zita-Met 50/500
(10 Tablets in a Strip)
Glenmark Pharmaceuticals Ltd
MRP Rs. 149.0
Rs. 14.9/Tablet
32.0%
Janumet (50/500Mg)
(14 Tablets in a Strip)
Merck Sharp & Dohme (MSD)
MRP Rs. 308.0
Rs. 22.0/Tablet
Janumet (50/500Mg)
(14 Tablets in a Strip)
Merck Sharp & Dohme (MSD)
MRP Rs. 308.0
Rs. 22.0/Tablet