Matilda Er Tab

(10 Tablets in Strip)
-10+
Tablet
(1 Strip)
Rs. 16.75 / Tablet
Rs.167.50

SALT INFORMATION

Folic Acid(5mg)

INDICATORS

Pregnancy:A Lactation:L1 Lab:NA Food:NA

TYPICAL USAGE

Folate-deficient. Megaloblastic anaemia. Prophylaxis of megaloblastic anemia in pregnancy. Prophylaxis of neural tube defect in pregnancy. Malabsorption syndromes. Antiepileptic therapy.

SIDE EFFECTS

Neuropathy, bronchospasm, itchy skin eruptions, malaise.

DRUG INTERACTION

Interacts with other drugs like deferoxamine, epoetin, fosphenytoin, methotrexate, sulphasalazine. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.

Methylcobalamin(1500mcg)

INDICATORS

Pregnancy:C Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

peripheral neuropathy, megaloblastic anaemia

SIDE EFFECTS

Anorexia, nausea, vomiting and diarrhoea.

DRUG INTERACTION

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives.

MECHANISM OF ACTION

Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Pyridoxine.(20mg)

INDICATORS

Pregnancy:B Lactation:L2 Lab:NA Food:NA

TYPICAL USAGE

Anaemia, Deficiency states, Idiopathic sideroblastic anaemia, Isoniazid neuropathy, Oedema and ascites in cirrhosis of the liver, Premenstrual syndrome, Schizophrenia and other psychoses, Vitamin deficiency.

SIDE EFFECTS

Dizziness, Drowsiness, Blurred vision, Pain, Burning.

DRUG INTERACTION

None mentioned.

MECHANISM OF ACTION

Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).

SUBSTITUTES

    No substitutes found