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Nervz G

(10 Tablets in a Strip)
Rs 109.16   per Strip Now Rs 109.16 YOU SAVE 0.0 %
10 Tablet  (1 Strip) Enter Pincode

Composition

SALTS:    Gabapentin (300mg) | Methylcobalamin (500mcg)

Salt Information

Gabapentin

Pregnancy: C Lactation: L3 Lab: NA Food: NA

Typical usage: Adjunctive therapy in the treatment of partial seizures with secondary generalisation. It is particularly useful in controlling secondarily generalised tonic-clonic seizures. Neuropathic pain.

Side Effects: Flatulence, dizziness, headache, drowsiness, fatigue, ataxia, anxiety, constipation, dry mouth, rashes, dyspepsia, depression, weight gain, somnolence, tremor, asthenia, nausea and vomiting.

Drug Interaction: Gabapentin is known to interact with other drugs like cimetidine (HCl), fosphenytoin, phenytoin (Na). These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Mechanism Of Action: Gabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium channels. Gabapentin increases the synaptic concentration of GABA, enhances GABA responses at non-synaptic sites in neuronal tissues, and reduces the release of mono-amine neurotransmitters. One of the mechanisms implicated in this effect of gabapentin is the reduction of the axon excitability measured as an amplitude change of the presynaptic fibre volley (FV) in the CA1 area of the hippocampus. This is mediated through its binding to presynaptic NMDA receptors.

Methylcobalamin

Pregnancy: C Lactation: L3 Lab: NA Food: NA

Typical usage: peripheral neuropathy, megaloblastic anaemia

Side Effects: Anorexia, nausea, vomiting and diarrhoea.

Drug Interaction: Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives.

Mechanism Of Action: Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

Substitutes

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NervonGm
(100 Tablets in a Pack)
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MRP Rs. 60.0
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95.0%
GabinM
(10 Tablets in a Strip)
Ind-Swift Limited
MRP Rs. 30.0
Rs. 3.0/Tablet
73.0%
Gabamin
(10 Tablets in a Strip)
Macleods Pharmaceuticals Pvt Ltd.
MRP Rs. 84.37
Rs. 8.44/Tablet
23.0%
Zincobal G
(10 Tablets in a Strip)
Zodley Pharmaceuticals Pvt Ltd
MRP Rs. 96.0
Rs. 9.6/Tablet
12.0%
CobanerveG
(10 Tablets in a Strip)
Invision Medi Sciences
MRP Rs. 97.0
Rs. 9.7/Tablet
11.0%
Showing 5 of 17