Pregnidoxin Tab

(10 x 1 in )
-10+
Tablet
(1 )
Rs. 1.34 / Tablet
Rs.13.40

SALT INFORMATION

Caffeine(20mg)

INDICATORS

Pregnancy:C Lactation:L5 Lab:NA Food:NA

TYPICAL USAGE

Nsaids, Antirheumatoid Drugs

SIDE EFFECTS

At doses > 600 mg per day, caffeine may cause anxiety, tachycardia (rapid heart rate), palpitations, insomnia, restlessness, nervousness, tremor and headache.

DRUG INTERACTION

Phenytoin and smoking may decrease caffeine levels.Cimetidine, disulfiram, fluoroquinolones, mexiletine, oral contraceptives may increase the caffeine levels, enhancing the effects.

MECHANISM OF ACTION

Caffeine increases energy metabolism throughout the brain but decreases at the same time cerebral blood flow, inducing a relative brain hypoperfusion. Caffeine activates noradrenaline neurons and seems to affect the local release of dopamine which in turm produces the Central Nervous System Stimulant effect.

Mesalazine(25mg)

INDICATORS

Pregnancy:C Lactation:L5 Lab:NA Food:NA

TYPICAL USAGE

Mild to moderate ulcerative colitis and maintenance of remission.

SIDE EFFECTS

Bronchospasm, nephrotic syndrome, blood dyscrasias, myocarditis, pericarditis, headache, nausea, vomiting, diarrhea, fever, rashes, hair loss, chest pain, leukopenia.

DRUG INTERACTION

Mesalazine is known to interact with other drugs like lactulose. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes and hydroxyeicosatetraenoic acids, is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalazine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon.

SUBSTITUTES

  • Pregnidoxin
    (15 Tablets in Tablet)
    Unichem Laboratories Ltd
    Rs. 1.61/Tablet
    Rs.24.10
    save -20%