Seloram 50/5

(14 Tablets in Strip)
-14+
Tablet
(1 Strip)
Rs. 26 / Tablet
Rs.364

SALT INFORMATION

Metoprolol(50MG)

INDICATORS

Pregnancy:D Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

Angina, cardiac arrhythmia, hypertension, hyperthyroidism (adjunct), maintenance of recurrent duodenal ulcers, migraine prophylaxis, myocardial infarction, prevention of relapse in duodenal ulcer.

SIDE EFFECTS

Agranulocytosis, hyperglycemia, severe bradycardia, bradycardia, dizziness, fatigue, nausea, vomiting, alopecia, diarrhea, dyspnea, pruritus, GI upset, elevation of liver enzymes, hyperpigmentation, sleep pattern disturbances.

DRUG INTERACTION

Metoprolol (Tartrate) is known to interact with other drugs like alprazolam, amiodarone (HCl), aspirin, benorylate, choline magnesium trisalicylate, cimetidine (HCl), clonidine (HCl), clorazepate (K), dexamphetamine (Sulphate), diltiazem (HCl), fluoxetine (HCl), fluvoxamine (Maleate). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Metoprolol competes with adrenergic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart. Beta(1)-receptor blockade results in a decrease in heart rate, cardiac output, and blood pressure.

Ramipril(5MG)

INDICATORS

Pregnancy:D Lactation:L4 Lab:NA Food:NA

TYPICAL USAGE

Benign gastric ulcer associated with H.pylori, Congestive heart failure (adjunct), Gastric acid reduction during anaesthesia, Heart failure, Hypertension, Iron deficiency anaemia, Mild to moderate hypertension, Prophylaxis of cardiovascular events/stroke.

SIDE EFFECTS

Dizziness, Headache, Diarrhea, Rashes, Nausea and vomiting.

DRUG INTERACTION

Non steroidal drugs may increase risk of deterioration of renal function.

MECHANISM OF ACTION

Ramipril is an ACE inhibitor which is metabolised into the active metabolite ramiprilat. It competitively inhibits angiotensin-converting enzyme (ACE) from converting angiotensin I to angiotensin II resulting in increased plasma renin activity and reduced aldosterone secretion. It also increases bradykinin levels. By these mechanisms, ramipril produces a hypotensive effect and a beneficial effect in CHF.

SUBSTITUTES

  • Prolomet R (50Mg)
    (10 Tablets in Tablet)
    Sun Pharmaceutical Industries Ltd.
    Rs. 16.20/Tablet
    Rs.162
    save 38%
  • Ace Revelol (50/5mg)
    (7 Tablets in Tablet)
    IPCA Laboratories Ltd
    Rs. 16.43/Tablet
    Rs.115
    save 37%