Nervup Forte

(10 Capsules in Strip)
-10+
Capsule
(1 Strip)
Rs. 7.61 / Capsule
Rs.76.14

SALT INFORMATION

Alpha Lipoic Acid(200 Mg)

INDICATORS

Pregnancy:C Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

Antioxitent

SIDE EFFECTS

Thiamine deficiency, low blood sugar levels.

DRUG INTERACTION

Alfa lipoic acid is known to interact with other drugs like metformin, glyburide. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Lipoic acid exists as two enantiomers, the R-enantiomer and the S-enantiomer. Normally only the R-enantiomer of an amino acid is biologically active, but for lipoic acid the S-enantiomer assists in the reduction of the R-enantiomer when a racemic mixture is given. The S-enantiomer has been found to reduce the expression of GLUT-4s in cells, responsible for glucose uptake, and hence reduce insulin sensitivity.

Folic Acid(0.5 Mg)

INDICATORS

Pregnancy:A Lactation:L1 Lab:NA Food:NA

TYPICAL USAGE

Folate-deficient. Megaloblastic anaemia. Prophylaxis of megaloblastic anemia in pregnancy. Prophylaxis of neural tube defect in pregnancy. Malabsorption syndromes. Antiepileptic therapy.

SIDE EFFECTS

Neuropathy, bronchospasm, itchy skin eruptions, malaise.

DRUG INTERACTION

Interacts with other drugs like deferoxamine, epoetin, fosphenytoin, methotrexate, sulphasalazine. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.

Methylcobalamin(500 Mcg)

INDICATORS

Pregnancy:C Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

peripheral neuropathy, megaloblastic anaemia

SIDE EFFECTS

Anorexia, nausea, vomiting and diarrhoea.

DRUG INTERACTION

Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives.

MECHANISM OF ACTION

Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.

SUBSTITUTES

    No substitutes found