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Angispan Tr (2.5 Mg)

(50 Tablets in a Pack)
Rs 103.5   per Pack Now Rs 103.5 YOU SAVE 0.0 %
50 Tablet  (1 Pack) Enter Pincode

Composition

SALTS:    Glyceryl Trinitrate (2.5 mg)

Salt Information

Glyceryl Trinitrate

Pregnancy: C Lactation: L5 Lab: NA Food: NA

Typical usage: Angina pectoris, cardiac failure, cardiopulmonary oedema, long-term treatment of healed reflux oesophagitis, moderate to severe reflux oesophagitis, myocardial infarction, oesophageal spasm, oesophageal spasm, postoperative hypertension, prinzmetal's angina.

Side Effects: Tachycardia, bradycardia, collapse, metabolic acidosis, cardiovascular collapse, syncope, neurologic deficit, methemoglobinemia, weakness, dizziness, headache, nausea, vomiting, restlessness, palpitation, abdominal pain, vertigo, urinary incontinence, syncope, fecal incontinence.

Drug Interaction: Angina pectoris, cardiac failure, cardiopulmonary oedema, long-term treatment of healed reflux oesophagitis, moderate to severe reflux oesophagitis, myocardial infarction, oesophageal spasm, oesophageal spasm, postoperative hypertension, prinzmetal's angina.

Mechanism Of Action: Nitroglycerin is converted to nitric oxide (NO), an active intermediate compound which activates the enzyme guanylate cyclase. This stimulates the synthesis of cyclic guanosine 3',5'-monophosphate (cGMP) which then activates a series of protein kinase-dependent phosphorylations in the smooth muscle cells, eventually resulting in the dephosphorylation of the myosin light chain of the smooth muscle fiber. The subsequent release of calcium ions results in the relaxation of the smooth muscle cells and vasodilation.

Substitutes

Vasovin (2.5 Mg)
(25 Tablets in a Strip)
Torrent Pharmaceuticals Ltd
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Gtn Sorbitrate 2.5Mg Tab
(25 Tablets in a Strip)
Abbott India Limited
MRP Rs. 97.8
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Nitract Sr (2.5Mg)
(25 Tablets in a Strip)
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MRP Rs. 141.0
Rs. 5.64/Tablet
-172.0%