Cardace H (5 Mg)

(10 Tablets in Strip)
-10+
Tablet
(1 Strip)
Rs. 14.98 / Tablet
Rs.149.80

SALT INFORMATION

Ramipril(5mg)

INDICATORS

Pregnancy:D Lactation:L4 Lab:NA Food:NA

TYPICAL USAGE

Benign gastric ulcer associated with H.pylori, Congestive heart failure (adjunct), Gastric acid reduction during anaesthesia, Heart failure, Hypertension, Iron deficiency anaemia, Mild to moderate hypertension, Prophylaxis of cardiovascular events/stroke.

SIDE EFFECTS

Dizziness, Headache, Diarrhea, Rashes, Nausea and vomiting.

DRUG INTERACTION

Non steroidal drugs may increase risk of deterioration of renal function.

MECHANISM OF ACTION

Ramipril is an ACE inhibitor which is metabolised into the active metabolite ramiprilat. It competitively inhibits angiotensin-converting enzyme (ACE) from converting angiotensin I to angiotensin II resulting in increased plasma renin activity and reduced aldosterone secretion. It also increases bradykinin levels. By these mechanisms, ramipril produces a hypotensive effect and a beneficial effect in CHF.

Hydrochlorothiazide (Immediate Release)(12.5mg)

INDICATORS

Pregnancy:B Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE

Disorders of calcium balance, Edema, Heart failure, Hypertension, Oedema, and can also be given in adjunctive therapy as an alternative drug of choice in Diabetes insipidus.

SIDE EFFECTS

Dizziness, Thirst, Headache, Nausea, Gout, Impotence, Polyuria, Night cramps.

DRUG INTERACTION

None mentioned.

MECHANISM OF ACTION

Hydrochlorothiazide, a thiazide diuretic, inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tubule, which is responsible for 5% of total sodium reabsorption.

SUBSTITUTES

    No substitutes found