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Drofem

(10 Tablets in a Strip)
Rs 41.0   per Strip Now Rs 41.0 YOU SAVE 0.0 %
10 Tablet  (1 Strip) Enter Pincode

Composition

SALTS:    Drotaverine (80mg) | Mefenamic Acid (250mg)

Salt Information

Drotaverine

Pregnancy: B Lactation: L2 Lab: NA Food: NA

Typical usage: Cholangitis, Cholecystitis, Cholecytolithiasis, Cystitis, Nephrolithiasis, Papilitis, Smooth muscle spasm, Stone formation, Ureterolithiasis, Urolithiasis, Vesical tenesmus.

Side Effects: Dizziness, Headache, Nausea, Palpitation, Constipation, Insomnia, Hypotension.

Drug Interaction: Not known

Mechanism Of Action: Drotaverine inhibits phosphodiesterases hydrolysing cAMP, thereby increasing cAMP concentration, decreasing Ca uptake of the cells and changing the distribution of calcium among the cells. It may also have minor allosteric calcium channel blocking properties.

Mefenamic Acid

Pregnancy: C Lactation: L3 Lab: NA Food: NA

Typical usage: Dysmenorrhoea, fever, inflammation, juvenile chronic arthritis, menorrhagia, migraine, musculoskeletal disorders, osteoarthritis, pain, post-operative pain, post-partum pain, rheumatoid arthritis.

Side Effects: Diarrhoea, peripheral edema, urticaria, GI bleeding, proteinuria, aplastic anemia, epidermal necrolysis, jaundice, nephrotic syndrome, interstitial nephritis, papillary necrosis, hemolysis, proctocolitis, enteritis, dizziness, headache, drowsiness, skin rashes, maculopapular rash, hematuria, elevation of liver enzymes.

Drug Interaction: Mefenamic acid is known to interact with other drugs like sulfapyridine, torasemide. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Mechanism Of Action: Mefenamic acid binds the prostaglandin synthetase receptors COX-1 and COX-2, inhibiting the action of prostaglandin synthetase. As these receptors have a role as a major mediator of inflammation or a role for prostanoid signaling in activity-dependent plasticity, the symptoms of pain are temporarily reduced.

Substitutes

Showing 5 of 17
Doxomax (400Mg)
(10 Tablets in a Strip)
Aristo Pharmaceuticals Pvt Ltd
MRP Rs. 38.27
Rs. 3.83/Tablet
7.0%
InrorineM
(50 Tablets in a Pack)
Ind-Swift Limited
MRP Rs. 205.0
Rs. 4.1/Tablet
Drofem
(10 Tablets in a Strip)
FDC Limited
MRP Rs. 45.0
Rs. 4.5/Tablet
-10.0%
Drotikind M
(10 Tablets in a Strip)
Mankind pharma
MRP Rs. 45.0
Rs. 4.5/Tablet
-10.0%
MdMf
(100 Tablets in a Pack)
Vensat
MRP Rs. 500.0
Rs. 5.0/Tablet
-22.0%
Showing 5 of 17