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There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Studies in breastfeeding mothers have demonstrated that there is significant and documented risk to the infant based on human experience, or it is a medication that has a high risk of causing significant damage to an infant. The risk of using the drug in breastfeeding women clearly outweighs any possible benefit from breastfeeding. The drug is contraindicated in women who are breastfeeding an infant.
Typical usage: It is used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure
Side Effects: Dizziness, back pain, sinusitis, pharyngitis and diarrhoea.
Drug Interaction: Telmisartan is known to interact with other drugs like acetylsalicylic acid, amifostine, amiloride, diclofenac, digoxin, fenoprofen, flurbiprofen, ketoprofen, ketorolac, lumiracoxib, meloxicam, nabumetone, spironolactone, tiaprofenic acid, tolmetin, trandolapril. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Mechanism Of Action: Telmisartan interferes with the binding of angiotensin II to the angiotensin II AT1-receptor by binding reversibly and selectively to the receptors in vascular smooth muscle and the adrenal gland. As angiotensin II is a vasoconstrictor, which also stimulates the synthesis and release of aldosterone and improve carbohydrate and lipid metabolism.
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