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Planep (25 Mg)

(10 Tablets in a Strip)
Rs 119.9   per Strip Now Rs 119.9 YOU SAVE 0.0 %
10 Tablet  (1 Strip) Enter Pincode


SALTS:    Eplerenone (25 mg)

Salt Information


Pregnancy: B Lactation: L5 Lab: NA Food: NA

Typical usage: Hypertension, congestive heart failure post MI, left ventricular dysfunction.

Side Effects: Angioneurotic edema, albuminuria, vaginal bleeding, gynecomastia, myocardial infarction, anaphylactic reactions, shortness of breath, dizziness, nausea, vomiting, diarrhea, hypotension, cough, light headedness.

Drug Interaction: Eplerenone is known to interact with other drugs like aspirin, diazoxide, enalapril (Maleate), erythromycin, ketoconazole, lithium. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Mechanism Of Action: Eplerenone binds to the mineralocorticoid receptor and thereby blocks the binding of aldosterone (component of the renin-angiotensin-aldosterone-system, or RAAS). Aldosterone synthesis, which occurs primarily in the adrenal gland, is modulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and potassium. Aldosterone binds to mineralocorticoid receptors in both epithelial (e.g., kidney) and nonepithelial (e.g., heart, blood vessels, and brain) tissues and increases blood pressure through induction of sodium reabsorption


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