MRP:Rs. 23.15 for 1 Strip(s) (10 Tablet each)
Discounted Price:Rs. 23.15 (0% OFF)
1

SALT INFORMATION

Spironolactone(50 mg)

TYPICAL USAGE

Spironolactone is used for treatment of edema (water retention) due to disease of heart , liver or kidney. It is a pottasium sparing diuretic (prevents loss of pottasium) and so used with other diuretics.

SIDE EFFECTS

Diarrhea, Drowsiness, Dizziness, Mental confusion.

DRUG INTERACTION

Sodium excretion effect may be inhibited by aspirin. May reduce ulcer-healing properties of carbenoxolone.

MECHANISM OF ACTION

Spironolactone acts on the distal renal tubules as a competitive antagonist of aldosterone. It increases the excretion of sodium chloride and water while conserving potassium and hydrogen ions.

Furosemide(20 mg)

TYPICAL USAGE

Furosemide is used for the treatment of edema (water retention) due to disease of heart, liver or kidney. It can also be used for relieving symptoms in acute left ventricular heart failure (inefficient working of left side of heart).

SIDE EFFECTS

Photosensitivity, Skin rashes, Ototoxicity, Nephrocalcinosis, Hyponatremia, Urinary retention, Dizziness, Blurred vision, Hypokalemia, Cardiac arrhythmias, CHO intolerance, Hypomagnesemia, Hyperosmolar non-ketotic precoma, deafness, Hypocalcemic tetany, Ototoxicity, Hypochloremic alkalosis.

DRUG INTERACTION

Furosemide is known to interact with other drugs like Aliskiren, Amikacin (Sulphate), Arbekacin, Caffeine, Calcium Gluconate, Captopril, Carbamazepine, Cefaclor (Monohydrate), Cefazolin, Cefotaxime, Ceftizoxime (Na).

MECHANISM OF ACTION

Furosemide inhibits reabsorption of Na and chloride mainly in the medullary portion of the ascending Loop of Henle. Excretion of potassium and ammonia is also increased while uric acid excretion is reduced. It increases plasma-renin levels and secondary hyperaldosteronism may result.

SUBSTITUTES

3 Substitutes
Sorted By
RelevancePrice
  • Fruselac
    (10 Tablet in Strip)
    Lupin Laboratories Ltd
    Rs. 2.27/Tablet
    Tablet
    Rs. 22.74
    save 2% more per Tablet
  • Fruselac
    (10 Tablet in Strip)
    Lupin Laboratories Ltd
    Rs. 2.70/Tablet
    Tablet
    Rs. 27
    pay 17% more per Tablet
  • Lasilactone
    (10 Tablet in Strip)
    Aventis Pharma India Ltd
    Rs. 2.76/Tablet
    Tablet
    Rs. 27.60
    pay 19% more per Tablet

INTERACTIONS

Can I take Amifru S during pregnancy?

Experiences of drug use and evidence from studies in pregnant women have shown risk to fetus. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Amifru S while breastfeeding/lactation?

Contraindicated: The drug should not be used by breastfeeding women, as evidences from studies have shown that there is a high risk of causing significant damage to infants.

Can I take Amifru S with alcohol?

No studies found