SALT INFORMATIONAminophylline(100 mg)
Acute severe asthma, asthma, obstructive airway disease, reversible airways obstruction.
Convulsions, hypoglycemia, hypovolemia, dizziness, headache, diarrhea, anxiety, restlessness, palpitation, tachycardia, tremors, insomnia, abdominal pain.
Aminophylline is known to interact with other drugs like allopurinol, ascorbic acid, cimetidine (HCl), disulfiram, fluvoxamine (Maleate), halothane, interferon alpha, ketamine (HCl), metipranolol, metrizamide, obidoxime (Cl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Aminophylline is the ethylenediamine salt of theophylline. After ingestion, theophylline is released from aminophylline, and theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction. In inflammatory states, theophylline activates histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones for transcription to begin.
- Aminophylline I.P(100mg)(10 Tablet in Strip)Cyper Drugs & PharmaceuticalRs. 0.09/TabletRs. 0.93save 42% more per Tablet
- Aminophylline (100mg)(10 Tablet in Strip)Shalina HealthcareRs. 0.10/TabletRs. 1save 37% more per Tablet
- Aminophylline (100mg)(1000 Tablet in Packet)Acichem LaboratoriesRs. 0.20/TabletRs. 200pay 25% more per Tablet
Can I take Aminophylline (100mg) during pregnancy?
Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.