Aminophylline (100mg)

Tablet
MRP:Rs. 160 for 1 Packet(s) (1000 Tablet each)
Discounted Price:Rs. 160 (0% OFF)
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Composition

Aminophylline(100 mg)

SALT INFORMATION

Aminophylline(100 mg)

TYPICAL USAGE

Acute severe asthma, asthma, obstructive airway disease, reversible airways obstruction.

SIDE EFFECTS

Convulsions, hypoglycemia, hypovolemia, dizziness, headache, diarrhea, anxiety, restlessness, palpitation, tachycardia, tremors, insomnia, abdominal pain.

DRUG INTERACTION

Aminophylline is known to interact with other drugs like allopurinol, ascorbic acid, cimetidine (HCl), disulfiram, fluvoxamine (Maleate), halothane, interferon alpha, ketamine (HCl), metipranolol, metrizamide, obidoxime (Cl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Aminophylline is the ethylenediamine salt of theophylline. After ingestion, theophylline is released from aminophylline, and theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction. In inflammatory states, theophylline activates histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones for transcription to begin.

SUBSTITUTES

3 Substitutes
Sorted By
RelevancePrice
  • Aminophylline I.P(100mg)
    (10 Tablet in Strip)
    Cyper Drugs & Pharmaceutical
    Rs. 0.09/Tablet
    Tablet
    Rs. 0.93
    save 42% more per Tablet
  • Aminophylline (100mg)
    (10 Tablet in Strip)
    Shalina Healthcare
    Rs. 0.10/Tablet
    Tablet
    Rs. 1
    save 37% more per Tablet
  • Aminophylline (100mg)
    (1000 Tablet in Packet)
    Acichem Laboratories
    Rs. 0.20/Tablet
    Tablet
    Rs. 200
    pay 25% more per Tablet

INTERACTIONS

Can I take Aminophylline (100mg) during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Aminophylline (100mg) while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Aminophylline (100mg) with alcohol?

No studies found