MRP:Rs. 10.95 for 1 Vial(s) (1 Powder for Injection each)
Discounted Price:Rs. 10.95 (0% OFF)
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Composition

Ampicillin + Cloxacillin(500mg)

SALT INFORMATION

Ampicillin + Cloxacillin(500mg)

TYPICAL USAGE

Gram positve bacteria, H-influenzae, E-coli, Proteus, Salmonella and Shigella, Strep.viridans, pneumococci, gonococci and meningococci.Urinary tract infections. Respiratory tract infections. Meningitis. Gonorrhoea. Cholecystitis. Subacute bacterial endocarditis. Septicaemias and mixed infections.

SIDE EFFECTS

Cholestatic jaundice, hemolytic anemia, blood dyscrasias, seizures, interstitial nephritis, cholestasis, neurotoxicity, rashes, fever, joint pain, eosinophilia, bronchial asthma, angioneuratic oedema, hemolytic anaemia, serum sickness.

DRUG INTERACTION

Failure of oral contraceptives, increased rash with allopurinol, reduced bactericidal activity with chloramphenicol, erythromycin and tetracyclines.

MECHANISM OF ACTION

Ampicillin exerts bactericidal action on both gm+ve and gm-ve organisms. Its spectrum includes gm+ve organisms eg, S pneumoniae and other Streptococci, L monocytogenes and gm-ve bacteria eg, M catarrhalis, N gonorrhoea. Ampicillin exerts its action by inhibiting the synthesis of bacterial cell wall. Cloxacillin is a penicillinase-resistant penicillin. Cloxacillin by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, cloxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is active against gm+ve organisms including penicillinase-producing strains of Staphylococci. Cloxacillin is highly active against Staph aureus, Strep pyogenes, Strep viridans and Strep pneumoniae. It is also active against penicillinase-producing gonococci and against N meningitidis and H influenzae.

SUBSTITUTES

10 Substitutes
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  • Dc (500mg)
    (1 Powder for Injection in Vial)
    Piramal Healthcare
    Rs. 7.55/Powder for Injection
    Powder for Injection
    Rs. 7.55
    save 31% more per Powder for Injection
  • Duoclox (500mg)
    (1 Powder for Injection in Vial)
    FDC Ltd
    Rs. 10.84/Powder for Injection
    Powder for Injection
    Rs. 10.84
    save 1% more per Powder for Injection
  • Uniclox (500mg)
    (1 Powder for Injection in Vial)
    Osper Formulations Pvt Ltd
    Rs. 7.70/Powder for Injection
    Powder for Injection
    Rs. 7.70
    save 30% more per Powder for Injection
  • 2pen (500mg)
    (1 Powder for Injection in Vial)
    Shrey Nutraceuticals & Herbals Pvt Ltd
    Rs. 8.91/Powder for Injection
    Powder for Injection
    Rs. 8.91
    save 19% more per Powder for Injection
  • Clompic Neonate(500mg)
    (1 Powder for Injection in Vial)
    Aglowmed Drugs Pvt. Ltd.
    Rs. 9.26/Powder for Injection
    Powder for Injection
    Rs. 9.26
    save 15% more per Powder for Injection

INTERACTIONS

Can I take Ampoxin (500mg) during pregnancy?

Studies in animals have shown no risk to the fetus, however there are no sufficient studies in humans. Patients should follow the advice of the doctor regarding its use. Patients should follow the advice of the doctor regarding its use.

Can I take Ampoxin (500mg) while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Ampoxin (500mg) with alcohol?

No studies found