Azotum (1000mg)

Powder for Injection
MRP:Rs. 465 for 1 Vial(s) (1 Powder for Injection each)
Discounted Price:Rs. 465 (0% OFF)
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Composition

Aztreonam(1000 mg)

SALT INFORMATION

Aztreonam(1000 mg)

TYPICAL USAGE

Septicemia/Bacteremia, Pyelonephritis and complicated urinary tract infection, Gram-negative lower respiratory tract infection. Gonorrhoea. Azitreonam is also used in other gram negative infections of skin soft tissue intra-abdominal including gynecological infections.

SIDE EFFECTS

Pseudomembranous colitis, eosinophilia, exfoliative dermatitis, nausea, vomiting, diarrhea, urticaria, thrombophlebitis, elevation of liver enzymes.

DRUG INTERACTION

If an aminoglycoside is used concurrently with aztreonam, especially if high dosages of the former are used or if therapy is prolonged, monitor renal function because of potential nephrotoxicity and ototoxicity of aminoglycoside antibiotics.

MECHANISM OF ACTION

The bactericidal action of aztreonam results from the inhibition of bacterial cell wall synthesis due to a high affinity of aztreonam for penicillin binding protein 3 (PBP3). By binding to PBP3, aztreonam inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that aztreonam interferes with an autolysin inhibitor.

SUBSTITUTES

8 Substitutes
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  • Aztreo (1000mg)
    (1 Powder for Injection in Vial)
    Zydus Cadila
    Rs. 450/Powder for Injection
    Powder for Injection
    Rs. 450
    save 3% more per Powder for Injection
  • Manvit (1000mg)
    (1 Powder for Injection in Vial)
    Mancure Drugs Pvt Ltd
    Rs. 460/Powder for Injection
    Powder for Injection
    Rs. 460
    save 1% more per Powder for Injection
  • Aztrone (1000mg)
    (1 Powder for Injection in Vial)
    Neon Laboratories Ltd
    Rs. 540/Powder for Injection
    Powder for Injection
    Rs. 540
    pay 16% more per Powder for Injection
  • Azvzn (1000mg)
    (1 Powder for Injection in Vial)
    Alwin Wilcare Pharmaceuticals
    Rs. 595/Powder for Injection
    Powder for Injection
    Rs. 595
    pay 28% more per Powder for Injection
  • Azenam (1000mg)
    (1 Powder for Injection in Vial)
    Aristo Pharmaceuticals Pvt Ltd
    Rs. 617/Powder for Injection
    Powder for Injection
    Rs. 617
    pay 33% more per Powder for Injection

INTERACTIONS

Can I take Azotum (1000mg) during pregnancy?

Studies in animals have shown no risk to the fetus, however there are no sufficient studies in humans. Patients should follow the advice of the doctor regarding its use. Patients should follow the advice of the doctor regarding its use.

Can I take Azotum (1000mg) while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Azotum (1000mg) with alcohol?

No studies found