MRP:Rs. 59 for 1 Strip(s) (2 Tablet each)
Discounted Price:Rs. 59 (0% OFF)
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Composition

Cabergoline(0.25 mg)

SALT INFORMATION

Cabergoline(0.25 mg)

TYPICAL USAGE

Excesssive prolactin level, lactation inhibition, parkinson's disease.

SIDE EFFECTS

Orthostatic hypotension, dizziness, fatigue, nausea, vomiting, confusion, ankle edema.

DRUG INTERACTION

Cabergoline is known to interact with other drugs like alcohol, clozapine, domperidone, erythromycin, levodopa, methyldopa, metoclopramide (HCl), octreotide (Acetate). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Cabergoline stimulates dopamine D2, causes inhibition of adenylyl cyclase, which decreases intracellular cAMP concentrations and blocks IP3-dependent release of Ca2+ from intracellular stores. Decreases in intracellular calcium levels may also be brought about via inhibition of calcium influx through voltage-gated calcium channels, rather than via inhibition of adenylyl cyclase. Additionally, receptor activation blocks phosphorylation of p42/p44 MAPK and decreases MAPK/ERK kinase phosphorylation. Inhibition of MAPK appears to be mediated by c-Raf and B-Raf-dependent inhibition of MAPK/ERK kinase. Dopamine-stimulated growth hormone release from the pituitary gland is mediated by a decrease in intracellular calcium influx through voltage-gated calcium channels rather than via adenylyl cyclase inhibition. Stimulation of dopamine D2 receptors in the nigrostriatal pathway leads to improvements in coordinated muscle activity in those with movement disorders.

SUBSTITUTES

9 Substitutes
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RelevancePrice
  • Cablyn (0.25mg)
    (4 Tablet in Strip)
    Celon Laboratories Ltd
    Rs. 22.50/Tablet
    Tablet
    Rs. 90
    save 24% more per Tablet
  • Cabgon (0.25tab)
    (2 Tablet in Strip)
    Intas Pharmaceuticals Ltd
    Rs. 22.50/Tablet
    Tablet
    Rs. 45
    save 24% more per Tablet
  • Cb Lin(0.25mg)
    (2 Tablet in Strip)
    Serum Institute Of India Ltd
    Rs. 25/Tablet
    Tablet
    Rs. 50
    save 15% more per Tablet
  • Caberlin (0.25mg)
    (4 Tablet in Strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 29.50/Tablet
    Tablet
    Rs. 118
    same price
  • Caberlin (0.25mg)
    (2 Tablet in Strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 29.50/Tablet
    Tablet
    Rs. 59
    same price

INTERACTIONS

Can I take Cabgolin (0.25mg) during pregnancy?

Studies in animals have shown no risk to the fetus, however there are no sufficient studies in humans. Patients should follow the advice of the doctor regarding its use. Patients should follow the advice of the doctor regarding its use.

Can I take Cabgolin (0.25mg) while breastfeeding/lactation?

Possibly unsafe: Evidence from studies in breastfeeding women show that there is a definite risk of side effects to the breastfed infants. However, use of the drug in breastfeeding women is acceptable in spite of the risk to the infants, if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective. Patients should follow the advice of the doctor regarding its use.

Can I take Cabgolin (0.25mg) with alcohol?

No studies found