It is used in the treatment of patient's with type 2 diabetes (non-insulin dependent diabetes). Metformin controls high level of sugar in the blood therefore prevents kidney damage, blindness and peripheral nerve problem.
The common side effects are urge to vomit, vomiting, diarrhea, abdominal pain, loss of appetite, malabsorption of vitamin B12, taste disturbance, and altered liver functions. Also, the patient may have the side effects of lactic acidosis (symptoms are vomiting, abdominal pain with muscle cramps, not feeling well with severe tiredness, and difficulty in breathing), and skin reactions such as redness of skin, itching, hives (pale red, raised, itchy bumps of skin).
Taking metformin with other anti-diabetic drugs may lead to excessive lowering of bloodsugar. If you go for an X-ray or scan, do not take metformin before and at least 48 hours afterwards. Metformin with diuretics (furosemide), anti-asthmatic drugs such as salbutamol or terbutaline, or corticosteroids (prednisone) may affect the glucose control. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Metformin decrease the level of glucose in the body by 1. Delays glucose absorption. 2. Decreases hepatic and renal glucose output. 3. Increases the peripheral glucose utilisation by enhancing anaerobic glycolysis (Breaking of sugar in the body). 4. Increasing the sensitivity of liver, muscle, fat, and other tissues to the uptake and effects of insulin.
To reduce high post meal glucose level in diabetes mellitus in patients who have been using other diabetic medications.
Diarrhea, loose stools, abdominal pain, constipation, loss of appetite, urge to vomit (nausea),vomiting, heartburn, increased gas, and intestinal obstruction like symptoms due to increased intestinal gas. Hypoglycemia, delay in digestion and absorption of disaccharides, fulminant hepatitis, serious liver dysfunction with increased liver enzymes, jaundice, anemia, numbness, edema, blurred vision, hot flushes, malaise, weakness, increased potassium levels, hyperkalemia, increased pancreatic enzyme (serum amylase).
Voglibose when used in combination with sulfonylamide, sulfonylurea, biguanide, insulin, atenolol, aspirin, symptoms associated with low blood sugar may occur. It also interacts with drugs like selegiline, warfarin, fenofibrate, epinephrine and thyroxine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Voglibose delays the digestion and absorption of carbohydrate in the intestine by inhibiting intestinal enzyme (alpha glucosidase) which results in reduction of increase in blood glucose level after meal.
- Vozuca M Activ(60 Tablet in Packet)Dr Reddy's Laboratories LtdRs. 1.04/TabletRs. 62.48save 87% more per Tablet
- Vozuca M(0.2active)(60 Tablet in Packet)Dr Reddy's Laboratories LtdRs. 3.27/TabletRs. 196save 59% more per Tablet
- Metadoze V(0.2mg)(10 Tablet in Strip)BioconRs. 3.55/TabletRs. 35.50save 56% more per Tablet
- Voglitor Mf(0.2mg)(10 Tablet in Strip)Torrent Pharmaceuticals LtdRs. 3.60/TabletRs. 36save 55% more per Tablet
- Starvog M(0.2mg)(10 Tablet in Strip)Zydus CadilaRs. 4.50/TabletRs. 45save 44% more per Tablet
Can I take Cetapin V(02mg) during pregnancy?
The drug should not be used by pregnant women. Experiences of drug use and evidence from studies in pregnant women have shown high risk to fetus. The risk of drug use in pregnant women outweighs the benefit.
Can I take Cetapin V(02mg) while breastfeeding/lactation?
Can I take Cetapin V(02mg) with alcohol?
Since there is some doubt about the results of concurrent use in this interaction, it is advised to give some guidance to the patient about its possible adverse effects and/or consider close monitoring.