Metformin is used in the treatment of diabetes mellitus, insulin resistance, and obesity.
The common side effects are urge to vomit, vomiting, diarrhea, abdominal pain, loss of appetite, malabsorption of vitamin B12, taste disturbance, and altered liver functions. Also, the patient may have the side effects of lactic acidosis (symptoms are vomiting, abdominal pain with muscle cramps, not feeling well with severe tiredness, and difficulty in breathing), and skin reactions such as redness of skin, itching, hives (pale red, raised, itchy bumps of skin).
Taking metformin with other anti-diabetic drugs may lead to excessive lowering of bloodsugar. If you go for an X-ray or scan, do not take metformin before and at least 48 hours afterwards. Metformin with diuretics (furosemide), anti-asthmatic drugs such as salbutamol or terbutaline, or corticosteroids (prednisone) may affect the glucose control. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
The exact mechanism of action of metformin is not clear but it appears to act by decreasing glucose absorption from the intestine, decreasing production of glucose from proteins and fats in liver, and enhancing insulin sensitivity in muscle by increasing glucose uptake and utilization.
To reduce high post meal glucose level in diabetes mellitus in patients who have been using other diabetic medications.
Diarrhea, loose stools, abdominal pain, constipation, loss of appetite, urge to vomit (nausea),vomiting, heartburn, increased gas, and intestinal obstruction like symptoms due to increased intestinal gas. Hypoglycemia, delay in digestion and absorption of disaccharides, fulminant hepatitis, serious liver dysfunction with increased liver enzymes, jaundice, anemia, numbness, edema, blurred vision, hot flushes, malaise, weakness, increased potassium levels, hyperkalemia, increased pancreatic enzyme (serum amylase).
Voglibose when used in combination with sulfonylamide, sulfonylurea, biguanide, insulin, atenolol, aspirin, symptoms associated with low blood sugar may occur. It also interacts with drugs like selegiline, warfarin, fenofibrate, epinephrine and thyroxine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Voglibose delays the digestion and absorption of carbohydrate in the intestine by inhibiting intestinal enzyme (alpha glucosidase) which results in reduction of increase in blood glucose level after meal.
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Can I take Cetapin V(02mg) during pregnancy?
The drug should not be used by pregnant women. Experiences of drug use and evidence from studies in pregnant women have shown high risk to fetus. The risk of drug use in pregnant women outweighs the benefit.
Can I take Cetapin V(02mg) while breastfeeding/lactation?
Can I take Cetapin V(02mg) with alcohol?
Since there is some doubt about the results of concurrent use in this interaction, it is advised to give some guidance to the patient about its possible adverse effects and/or consider close monitoring.