SALT INFORMATIONClarithromycin(250 mg)
URTI, pharyngitis and sinusitis, LRTI, bronchitis and pneumonia, skin and soft tissue infection. H.Pylori infection.Infection due to Mycobacterium avium complex (MAC).
Pseudomembranous colitis, renal failure, interstitial nephritis, headache, nausea, vomiting, diarrhea, abdominal pain, phlebitis, glossitis, stomatitis.
Clarithromycin is known to interact with other drugs like alprazolam, artesunate, astemizole, carbamazepine, cimetidine (HCl), cisapride, cyclosporin A, digoxin, dihydroergotamine (Mesylate), disopyramide, ergotamine (Tartrate), erlotinib, fluoxetine (HCl), isosorbide (Dinitrate), loratadine, lorazepam, lovastatin.
MECHANISM OF ACTION
Clarithromycin is first metabolized to 14-OH clarithromycin, which is active and works synergistically with its parent compound. Like other macrolides, it then penetrates bacteria cell wall and reversibly binds to domain V of the 23S ribosomal RNA of the 50S subunit of the bacterial ribosome, blocking translocation of aminoacyl transfer-RNA and polypeptide synthesis. Clarithromycin also inhibits the hepatic microsomal CYP3A4 isoenzyme and P-glycoprotein, an energy-dependent drug efflux pump.
- Clarivir (250mg)(10 Tablet in Strip)East African India Remedies Pvt LtdRs. 2.40/TabletRs. 24save 88% more per Tablet
- Clarwin (250mg)(10 Tablet in Strip)Micro Labs Ltd (Brown & Burk )Rs. 7.44/TabletRs. 74.36save 62% more per Tablet
- Clarit (250mg)(4 Tablet in Strip)Finecure Pharmaceuticals LtdRs. 12/TabletRs. 48save 39% more per Tablet
- Clar (250mg)(4 Tablet in Strip)Lyka Labs LtdRs. 18.25/TabletRs. 73save 7% more per Tablet
- Bioclar (250mg)(10 Tablet in Strip)Biochem Pharmaceutical IndustriesRs. 14.94/TabletRs. 149.40save 24% more per Tablet
Can I take Claribid (250mg Tab 10mg) during pregnancy?
Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.