MRP:Rs. 66 for 1 Strip(s) (10 Tablet each)
Discounted Price:Rs. 66 (0% OFF)
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Composition

Clomipramine(25 mg)

SALT INFORMATION

Clomipramine(25 mg)

TYPICAL USAGE

Edogenous depression. Obsessive compulsive neurosis and phobic states.

SIDE EFFECTS

Parkinsonism, jaundice, seizures, extrapyramidal symptoms, bone marrow depression, hypertension, vomiting, tachycardia, convulsions, coma, drowsiness, ataxia, mydriasis, agitation, restlessness, impaired impulse conduction, headache, drowsiness, fatigue, ataxia, fever, anxiety, palpitation, tremors, abdominal pain, blurred vision, confusion, pruritus, erythema, sedation, photosensitivity, hallucination, weight gain, disorientation, reduced salivation, micturition.

DRUG INTERACTION

Clomipramine is known to interact with other drugs like adrenaline, alcohol, amiodarone (HCl), antazoline, apraclonidine (HCl), cimetidine (HCl), clonidine (HCl), fluoxetine (HCl), fluvoxamine (Maleate).

MECHANISM OF ACTION

Clomipramine is a strong, but not completely selective serotonin reuptake inhibitor (SRI), as the active main metabolite desmethyclomipramine acts preferably as an inhibitor of noradrenaline reuptake. ?1-receptor blockage and ?-down-regulation have been noted and most likely play a role in the short term effects of clomipramine. A blockade of sodium-channels and NDMA-receptors might, as with other tricyclics, account for its effect in chronic pain, in particular the neuropathic type.

SUBSTITUTES

21 Substitutes
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  • Clomifril (25mg)
    (10 Tablet in Strip)
    Torrent Pharmaceuticals Ltd
    Rs. 2.90/Tablet
    Tablet
    Rs. 29.05
    save 56% more per Tablet
  • Clomidac (25mg)
    (10 Tablet in Strip)
    Zydus Cadila
    Rs. 2.95/Tablet
    Tablet
    Rs. 29.50
    save 55% more per Tablet
  • Depnil (25mg)
    (10 Tablet in Strip)
    Cipla Ltd
    Rs. 3.10/Tablet
    Tablet
    Rs. 31
    save 53% more per Tablet
  • Clo (25mg)
    (10 Tablet in Strip)
    Orchid Chemicals & Pharmaceuticals Ltd
    Rs. 3.12/Tablet
    Tablet
    Rs. 31.20
    save 53% more per Tablet
  • Anafranil (25mg)
    (10 Tablet in Strip)
    Novartis Pharmaceuticals Ltd
    Rs. 4.99/Tablet
    Tablet
    Rs. 49.90
    save 24% more per Tablet

INTERACTIONS

Can I take Clofranil (25mg) during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Clofranil (25mg) while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Clofranil (25mg) with alcohol?

No studies found