SALT INFORMATIONBisoprolol(1.25 mg)
Adjunct in stable moderate to severe heart failure, angina, arterial hypertension, cardiac arrhythmia, hyperthyroidism.
Bronchospasm, decreased cardiac performance, cardiogenic shock, bradycardia, AV-block, necrosis of extremities, dizziness, tiredness, headache, cold extremities, sweating, impotence, weakness of the leg.
Bisoprolol is known to interact with other drugs like adrenaline, amiodarone (HCl), cimetidine (HCl), clonidine (HCl), digoxin, diltiazem (HCl), indomethacin, naproxen, nifedipine, rifampicin, theophylline, verapamil (HCl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Bisoprolol selectively blocks catecholamine stimulation of beta1-adrenergic receptors in the heart and vascular smoothmuscle. This results in a reduction of heart rate, cardiac output, systolic and diastolic blood pressure, and possibly reflex orthostatic hypotension.
SUBSTITUTESNo substitutes found
Can I take Concor Cor(1.25mg) during pregnancy?
Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.