Eptoin (100mg)

Tablet
MRP:Rs. 166.30 for 1 Packet(s) (100 Tablet each)
Discounted Price:Rs. 166.30 (0% OFF)
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Composition

Phenytoin(100 mg)

SALT INFORMATION

Phenytoin(100 mg)

TYPICAL USAGE

Convulsions, epilepsy, migraine prophylaxis, myotonia, prophylaxis of epilepsy, status epilepticus, status epilepticus; seizures in neurosurgery, TIC douloureaux, ventricular arrhythmias.

SIDE EFFECTS

Ataxia, nausea, vomiting, hypotension, drowsiness, nystagmus, coma, hyperglycemia, stupor, blurred vision, skin rashes, elevated alkaline phosphatase, folate deficiency, hypocalcemia.

DRUG INTERACTION

Phenytoin sodium is known to interact with other drugs like abacavir, abiraterone acetate, aceclofenac, acetazolamide (Na), acyclovir, alcohol, alcuronium (Cl), alfacalcidol, allopurinol, alprazolam, amiodarone (HCl), amitriptyline (HCl), amlodipine (Besylate), amoxapine, amprenavir, artesunate, aspirin, auranofin, azapropazone, bamifylline, beclomethasone (Dipropionate), benorylate, betamethasone, bleomycin, bromazepam, bupropion (HCl), busulphan, caffeine, calcifediol, carbamazepine, chloramphenicol, chlordiazepoxide (HCl), chlorpheniramine (Maleate), chlorpromazine (HCl), chlorpropamide, cholecalciferol, choline magnesium trisalicylate, cimetidine (HCl), ciprofloxacin, clarithromycin, clobazam, clofibrate, clomipramine (HCl), clonazepam, clopidogrel, clozapine, co-trimoxazole, corticotropin, cortisone (Acetate), cyclosporin A. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Phenytoin acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. By promoting sodium efflux from neurons, phenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. This includes the reduction of post-tetanic potentiation at synapses. Loss of post-tetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas.

SUBSTITUTES

17 Substitutes
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  • Phenykem (100mg)
    (100 Tablet in Packet)
    Alkem Laboratories Ltd
    Rs. 1.50/Tablet
    Tablet
    Rs. 150
    save 10% more per Tablet
  • Epsolin Tabs
    (100 Tablet in Packet)
    Cadila Pharmaceuticals Ltd
    Rs. 1.51/Tablet
    Tablet
    Rs. 151.50
    save 9% more per Tablet
  • Phenykem (100mg)
    (10 Tablet in Strip)
    Alkem Laboratories Ltd
    Rs. 1.71/Tablet
    Tablet
    Rs. 17.15
    pay 3% more per Tablet
  • Epsolin Er(100mg)
    (30 Tablet in Packet)
    Zydus Cadila
    Rs. 2.63/Tablet
    Tablet
    Rs. 79
    pay 58% more per Tablet
  • Epileptin (100mg)
    (10 Tablet in Strip)
    Indian Drugs & Pharmaceuticals Ltd
    Rs. 0.80/Tablet
    Tablet
    Rs. 8
    save 52% more per Tablet

INTERACTIONS

Can I take Eptoin (100mg) during pregnancy?

Experiences of drug use and evidence from studies in pregnant women have shown risk to fetus. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Eptoin (100mg) while breastfeeding/lactation?

Possibly unsafe: Evidence from studies in breastfeeding women show that there is a definite risk of side effects to the breastfed infants. However, use of the drug in breastfeeding women is acceptable in spite of the risk to the infants, if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective. Patients should follow the advice of the doctor regarding its use.

Can I take Eptoin (100mg) with alcohol?

No studies found