Amlodipine is used to treat high blood pressure and various forms of angina (severe pain in chest which may travel into the jaw, neck and arms or narrowing of the coronary arteries of the heart.
The common side effects are headache, swelling of part or whole of body, rash, unusual tiredness, urge to vomit, facial redness and feeling of warmth (flushing), sleepiness, dizziness, headache, swelling of ankle, face, lips and eyes, sleepiness, abdominal pain, indigestion, drowsiness, and thumping, pounding or fluttering sensation in the chest
Grapefruit juice may increase plasma concentration of amlodipine. Amlodipine may cause excessive reduction in blood pressure on interaction with calcium, sildenafil, tadalafil or vardenafil. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Amlodipine is an anti-hypertensive drug that relaxes and opens blood vessels, thus, improving the flow of blood and lowering the blood pressure. It improves blood and oxygen supply to the heart muscles.
To control high blood pressure, prevent chest pain, control heart rhythm disorders and prevention of severe headache (migraine).
Narrowing of airways, wheezing, slowing of heart rate, low blood pressure, heart failure, heart block, cold hands and feet, feeling tired and weak, dizziness, confusion, drowsiness, feeling depressed, urge to vomit (nausea), diarrhea, constipation, and inability to maintain erection (sexual dysfunction).
NSAIDs such as ibuprofen, naproxen and calcium channel blockers (verapamil, nifedipine and diltiazem) taken with atenolol can severely lower blood pressure and reduce heart rate. Atenolol when administered with antiarrhythmic drugs (disopyramide, amiodarone), digoxin can cause severe lowering of heart rate. Use of other hypotensive with atenolol can cause excess lowering of blood pressure. Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can decrease the heart rate (bradycardia). Administration with insulin or other oral anti-diabetics can impair sugar control. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Atenolol blocks beta receptors (beta blockers) in the heart and peripheral blood vessels resulting in slowing of heart rate and relaxing of blood vessels thereby lowering blood pressure. Atenolol reduces oxygen requirement at any level of activity making it useful for long-term management of heart attacks caused by restricted cardiac blood flow.
- Eslo At(10 Tablet in Strip)Zuventus Healthcare LtdRs. 7.25/TabletRs. 72.48pay 83% more per Tablet
- Asomex At(2.5mg)(10 Tablet in Strip)Emcure Pharmaceuticals LtdRs. 7.55/TabletRs. 75.50pay 91% more per Tablet
- Asomex At(25mg)(10 Tablet in Strip)Emcure Pharmaceuticals LtdRs. 7.99/TabletRs. 79.90pay 102% more per Tablet
- Numlo At(10 Tablet in Strip)Emcure Pharmaceuticals LtdRs. 8.69/TabletRs. 86.90pay 120% more per Tablet
Can I take Espin At during pregnancy?
Experiences of drug use and evidence from studies in pregnant women have shown risk to fetus. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.