Hyponat O(15tab 10)

Tablet
MRP:Rs. 318.70 for 1 Strip(s) (10 Tablet each)
Discounted Price:Rs. 318.70 (0% OFF)
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Composition

Tolvaptan(15 mg)

SALT INFORMATION

Tolvaptan(15 mg)

TYPICAL USAGE

It is used to treat hyponatremia (low sodium concentration in the blood) in patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH) (excessive levels of antidiuretic hormones).

SIDE EFFECTS

Asthenia, constipation, dry mouth, hyperglycemia, pollakiuria, polyuria, thirst, anorexia, nausea.

DRUG INTERACTION

Tolvaptan is known to interact with other drugs like barbital, bicalutamide, carbamazepine, conivaptan, digoxin, erythromycin, fluconazole, itraconazole, ketoconazole, phenytoin, rifabutin, ritonavir, verapamil. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Tolvaptan is a selective and competitive arginine vasopressin receptor 2 antagonist. Vasopressin acts on the V2 receptors found in the walls of the vasculature and luminal membranes of renal collecting ducts. By blocking V2 receptors in the renal collecting ducts, aquaporins do not insert themselves into the walls thus preventing water absorption. This action ultimately results in an increase in urine volume, decrease urine osmolality, and increase electrolyte-free water clearance to reduce intravascular volume and an increase serum sodium levels.

SUBSTITUTES

7 Substitutes
Sorted By
RelevancePrice
  • Natrise Tab
    (4 Tablet in Strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 24.75/Tablet
    Tablet
    Rs. 99
    save 22% more per Tablet
  • Hyponat O(30tab)
    (10 Tablet in Strip)
    Cadila Pharmaceuticals Ltd
    Rs. 49/Tablet
    Tablet
    Rs. 490
    pay 54% more per Tablet
  • Natrise (15mg)
    (4 Tablet in Strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 99/Tablet
    Tablet
    Rs. 396
    pay 211% more per Tablet
  • Natrise (15tab)
    (4 Tablet in Strip)
    Sun Pharmaceutical Industries Ltd
    Rs. 99/Tablet
    Tablet
    Rs. 396
    pay 211% more per Tablet
  • Tvaptan (15mg)
    (4 Tablet in Strip)
    Centaur Pharmaceuticals Pvt Ltd
    Rs. 99/Tablet
    Tablet
    Rs. 396
    pay 211% more per Tablet

INTERACTIONS

Can I take Hyponat O(15tab 10) during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Hyponat O(15tab 10) while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Hyponat O(15tab 10) with alcohol?

No studies found