Lumacip Plus Cream(15gm)

Cream
MRP:Rs. 185 for 1 Tube(s) (15 g Cream each)
Discounted Price:Rs. 185 (0% OFF)
1

SALT INFORMATION

Hydroquinone(4%w /w)

TYPICAL USAGE

dark patches

SIDE EFFECTS

Transient erythema, mild burning sensations, hyperpigmentation. Staining and corneal opacities. Tremors and convulsions after systemic absorption. Occasionally, hypersensitivity.

DRUG INTERACTION

Do not start, stop, or change the dosage of any medicine before check with your doctor or pharmacist first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

MECHANISM OF ACTION

Hydroquinone is a topical depigmentating agent used in hyperpigmentation conditions by suppressing melanocyte metabolic processes. It also increases melanin excretion from melanocytes and prevents its production.

Tretinoin(0.05%w /w)

TYPICAL USAGE

Acne vulgaris, promyelocytic leukemia.

SIDE EFFECTS

Erythema, irritation, warmth feeling.

DRUG INTERACTION

Tretinoin is known to interact with other drugs like alcohol, benzoyl peroxide, minoxidil, resorcinol, retinol (Vitamin A), salicylic acid, sulphur. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Tretinoin stimulates mitosis and turnover of follicular epithelial cells and reduce their cohesiveness. This facilitates extrusion of existing comedones and prevents formation of new comedone. It also exhibits thinning effect on the stratum corneum. In acute promyelocytic leukaemia, it induces cellular differentiation and decreases proliferations.

Fluocinolone(0.01%w /w)

TYPICAL USAGE

asthma attacks

SIDE EFFECTS

Telangiectasia, striae, glaucoma, cataract, growth retardation, adrenal suppression, epidermal thinning, raised intracranial pressure, allergic reactions, perioral dermatitis, rebound pustulation.

DRUG INTERACTION

Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of oral corticosteroids (e.g., prednisone), drugs that suppress the immune system (e.g., cyclosporine).

MECHANISM OF ACTION

Fluocinonide binds to the cytosolic glucocorticoid receptor. After binding the receptor the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing the increase in expression of specific target genes. The anti-inflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. Specifically glucocorticoids induce lipocortin-1 (annexin-1) synthesis, which then binds to cell membranes preventing the phospholipase A2 from coming into contact with its substrate arachidonic acid. This leads to diminished eicosanoid production.

SUBSTITUTES

No substitutes found

INTERACTIONS

Can I take Lumacip Plus Cream(15gm) during pregnancy?

Experiences of drug use and evidence from studies in pregnant women have shown risk to fetus. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Lumacip Plus Cream(15gm) while breastfeeding/lactation?

Contraindicated: The drug should not be used by breastfeeding women, as evidences from studies have shown that there is a high risk of causing significant damage to infants.

Can I take Lumacip Plus Cream(15gm) with alcohol?

No studies found