Lumacip Plus Cream(15gm)

Cream
MRP:Rs. 185 for 1 Tube(s) (15 g Cream each)
Discounted Price:Rs. 185 (0% OFF)
1

SALT INFORMATION

Hydroquinone(4%w /w)

TYPICAL USAGE

Hydroquinone is used to gradually lighten the  skin that has become dark or skin that has developed dark patches due to many skin problems. These incluse melasma – skin darkening due to exposure to sunlight especially in women using oral contraceptives (birth control pills), during pregnancy, or on hormone replacement therapy during menopause (hormonal drugs to replace deficient hormones in the body), freckles (clusters of dark spots on cheeks, nose, arms, and upper shoulders that start appearing at a very young age) and solar lentigines (also called ‘age spots’ are brown or black spots on the face, hands, shoulders and arms – areas that get exposed to sun light)

SIDE EFFECTS

* Mild to moderate irritation * Allergic skin reaction – red, sore, itchy, inflamed skin (contact dermatitis) may occur occasionally. Discontinue use and contact your doctor immediately if you experience any skin reaction

DRUG INTERACTION

* There are no known drug interactions for hydroquinone creams  * Please inform your doctor about all the medications, herbal and dietary supplements you are currently using to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects. * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Hydroquinone bleaches the skin by reducing the accumulation of skin pigment called melanin that causes darkening of skin. It interferes with the synthesis of melanin and hampers important processes within cells that produce melanin (melanocytes). The bleaching effect of hydroquinone is reversible (reversible depigmentation).

DOSAGE

Always follow the instructions of doctor regarding the dosage and duration * Adults: Apply hydroquinone cream to the affected area twice daily or as advised by your doctor * Children: Use in children aged below 12 years is not recommended unless under the strict supervision of doctor

DOs and DON'Ts

* Please use hydroquinone products carefully. Its skin bleaching action may produce unwanted cosmetic effects if not used as directed. * Use of sunscreen is a must while using hydroquinone. Avoid unnecessary sun exposures and cover the treated areas with clothing. Even minimal exposure to sunlight can reverse the bleaching effect of hydroquinone. * Discontinue use and contact your doctor immediately if you develop allergic skin reaction or notice blue-black darkening of skin upon use of hydroquinone.  * Hydroquinone creams are meant for external use on the skin only. Immediately wash-off with water, if the cream gets into your eyes, nose, mouth, or on your lips. * Do not use hydroquinone creams on broken, irritated or injured skin * Do not use hydroquinone creams with other creams that contain peroxides (hydrogen peroxide/benzoyl peroxide). This may produce a dark stain on your skin which can be removed by stopping the use of peroxides and washing with soap and water. * Do not use hydroquinone creams with other creams that contain resorcinol, phenol, or salicylic acid unless advised by your doctor. * Please check if the hydroquinone cream contains sulfites. Such products may trigger allergic reactions in individuals with asthma. * You may be advised by your doctor to perform a skin sensitivity test to avoid any allergic reaction. * Do consult your doctor before using hydroquinone if you are pregnant or planning to become pregnant or breastfeeding.

CONTRA INDICATIONS

Patients with a history of severe allergic reaction to hydroquinone or any other ingredient in the medicine.

FAQ

Q. Is hydroquinone safe/good for skin? Yes. Hydroquinone is used to bleach dark patches of skin. It is available as creams to be applied externally and is safe if used as directed, for the prescribed duration by your doctor. Occasionally it may cause side effects – red, sore, itchy, inflamed skin indicating an allergic reaction. Please contact your doctor immediately if you notice any such skin reactions.Q. Is hydroquinone a steroid?No. Hydroquinone does not have a structure or effect similar to steroids.Q.Is hydroquinone safe to use on face?Yes. Hydroquinone is used to bleach dark patches of skin and can be used on the face. It is available as creams to be applied externally and is safe if used as directed for the prescribed duration by your doctor. Please limit sun exposures and apply sunscreens or cover the treated area with protective clothing. Even minimal exposure to sun can reverse the bleaching effect of hydroquinone.Q. Is hydroquinone banned in India?No. Hydroquinone is available and is not a banned drug in India.Q. Is hydroquinone carcinogenic/does hydroquinone cause cancer?Studies of hydroquinone in animals have indicated some evidences of cancer causing potential (carcinogenicity). However, the carcinogenic effects in human are not known.Q. Is hydroquinone toxic?No. Hydroquinone is not toxic if used as directed, for the prescribed duration by your doctor. It is available as creams and meant for external use on the skin onlyQ. Does hydroquinone lighten/bleach your skin? Does hydroquinone lighten skin permanently?Hydroquinone bleaches/lightens dark patches of skin. It reduces the accumulation of skin pigment called melanin that causes darkening of skin. This effect of hydroquinone is reversible (reversible depigmentation) with time and exposure to sun and therefore not permanent.Q. Does hydroquinone bleach clothes?No. Hydroquinone has no known effect on bleaching clothes. Q. Does hydroquinone make skin darker?Hydroquinone may cause blue-black darkening of skin. This is not the normal effect of hydroquinone. Discontinue use and contact your doctor immediately if you notice darkening of skin upon use of hydroquinone. Q. Does hydroquinone help acne?No. Hydroquinone is used to bleach or lighten dark patches of skin. It has no known effect in the treatment of acne.Q. Does hydroquinone cause redness?Occasionally hydroquinone may cause side effects – redness of skin, sore, itchy, inflamed skin indicating an allergic reaction. Please contact your doctor immediately if you notice any such skin reactions.

FURTHER INFORMATION

1. Prescribing information www.vitivia.com/images/aclaropd-pi.pdf 2. Prescribing information  (combination)     www.accessdata.fda.gov/drugsatfda_docs/label/.../021112s006lbl.pdf 3. http://www.drugs.com/mtm/hydroquinone-topical.html

Tretinoin(0.05%w /w)

TYPICAL USAGE

Tretinoin is topically used to treat acne, smooth rough facial skin, reduce the appearance of fine wrinkles and mottled skin discoloration. It is also used to treat a type of blood problem called acute promyelocytic leukaemia (bone marrow malignancy with an excess of immature cell) 

SIDE EFFECTS

* Very common: hair loss, an irregular heartbeat, changes to your eyesight or hearing, bone or joint pain, chest pain or abdominal pain, skin rash, itching, redness, peeling or inflammation, dry skin, mouth or nose, swollen, dry or cracked lips, breathing difficulties such as asthma, conjunctivitis or dry eyes, difficulty sleeping, sweating, headache or feeling dizzy, feeling tired, cold or generally unwell, feeling confused, worried or depressed, pins and needles or numbness of your hands or feet, loss of appetite, feeling or being sick, stomach upset, diarrhea or constipation, higher levels of blood fats (triglycerides and cholesterol) * Frequency not known: genital ulcers, serious bacterial infections, kidney problems (renal infarct), swollen muscles or swollen blood vessels (vasculitis), red painful lumps under the skin (erythema nodosum),loss of appetite, feeling drowsy or weak (possible sign of too much calcium in your blood, too many platelets (thrombocythaemia), a change in the number of white blood cells (basophilia) or increased histamine levels * Common side effects of tretinoin cream or gel (for topical use): increase or decrease of skin pigment (color); redness, peeling, or feeling of warmth; sensitivity to sunlight; skin irritation; stinging at the application site.

DRUG INTERACTION

Avoid concomitant and systemic use of tretinoin with the following medicines: * tetracyclines (a type of antibiotic) * vitamin A * low-dose progestogens for birth control (mini-pill)Medicines which may require particular care when taken with tretinoin include: * rifampicin and erythromycin (antibiotics) * pentobarbital (for insomnia) * cimetidine (for stomach ulcers) * verapamil and diltiazem (for heart conditions or high blood pressure) * ciclosporin (used following organ or bone marrow transplants) * tranexamic acid, aminocaproic acid and aprotinin (used to reduce bleeding) * corticosteroids (used in the treatment of asthma or other inflammation treatments) * ketoconazole, itraconazole (used in antifungal treatment) * phenytoin, phenobarbital, carbamazepine (used in the treatment of fits) * Pain killers and aspirin Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Tretinoin is a form of vitamin A and belongs to a group of medicines called ‘retinoids’. It helps the skin renew itself and works by slowing the growth of certain types of diseased blood cells.

DOSAGE

Always follow the instructions of doctor regarding the dosage and duration:  Acute promyelocytic leukaemia: * Adults and children: 45 mg/m2. 8 capsules a day divided into two equal doses * Adults with kidney or liver diseases:  25 mg/m2 divided into two equal doses dailyMaximum period of treatment is 90 daysTretinoin cream for topical use: * Use once a day as directed by your physician or as in packaging leaflet

DOs and DON'Ts

Do not take tretinoin and tell your doctor: * If you are allergic to tretinoin or any of the other ingredients or other ‘retinoid’ medicines (isotretinoin, acitretin and tazarotene) and peanuts or soya (as tretinoin medicines may contain soyabean oil). * If you are pregnant, planning to become pregnant or breastfeedingDo not drive or operate or drive machinery while you are taking tretinoin * Avoid becoming pregnant during and within one month (four weeks) after stopping treatment with tretinoin. Consult your doctor for the right method of contraception you can use. * Avoid getting tretinoin cream in your eyes, nose, or mouthTretinoin cream may cause you to become sunburned more easily. Take suitable precautions (sun cream, clothing etc.). Do not apply tretinoin cream to sunburned skin * Do not stop using tretinoin if your skin condition appears to worsen for the first 2 to 3 weeks of treatment. This is expected.  * Talk with your doctor before you use any other medicines or products on your skin.  * Tretinoin should be used extreme caution in children younger than 12 years old.

CONTRA INDICATIONS

Do not take tretinoin: * If you are allergic to tretinoin or any of the other ingredients or other ‘retinoid’ medicines (isotretinoin, acitretin and tazarotene) and peanuts or soya (as tretinoin medicines may contain soyabean oil). * If you are pregnant, planning to become pregnant or breastfeeding * If you are taking a tetracycline (a type of antibiotic) * If you are taking vitamin A * If you have any other allergies or any other illness

FAQ

Q. Is tretinoin a steroid/ retin a/ retin a/ a retinoid/retinol?Tretinoin is not a steroid. It is a form of vitamin A (Retin-A) and belongs to a group of medicines called ‘retinoids’. Tretinoin and retinol are similar but tretinoin tends to be a bit more aggressive than retinol which is a bit more suitable for those with sensitive skin.Q. Is tretinoin safe/ tretinoin cream safe?Tretinoin is safe if taken at recommended doses and duration. The gel form should be used with extreme caution in children younger than 12 years.Q. Does tretinoin cream work/ is tretinoin cream good for acne/acne scars/ lighten skin/thin the skin/work on wrinkles/fade dark spots/clog pores/ cause breakouts?Tretinoin cream works effectively in most of the patients. It is useful for treating most of the skin related issue like acne, acne scars, skin lightening, removing wrinkles, fade dark spots, clog pores, etc. It does not cause breakouts but helps the skin in healing it. Q. Is tretinoin available over the counter?It is available only as per doctor’s prescription.Q. Does tretinoin stain clothes?It may stain as it has a preservative in it.

FURTHER INFORMATION

* Summary of product characteristics: https://www.medicines.org.uk/emc/medicine/28341 * Patient information leaflet :   https://www.medicines.org.uk/emc/PIL.28332.latest.pdf * http://www.drugs.com/cdi/tretinoin-cream.html

Fluocinolone(0.01%w /w)

TYPICAL USAGE

Fluocinolone is used to reduce inflammation of the eye caused by various diseases, particularly diabetes (diabetic macular edema). It is also used to treat various skin infections such as eczema and psoriasis.

SIDE EFFECTS

* Very Common: cataract, increased intraocular pressure, floaters. * Common: increased pressure inside the eye (glaucoma), eye pain, blurred vision, reduced visual acuity, conjunctival hemorrhage, vitreous haemorrhage, glaucoma surgery, trabeculoplasty. * Uncommon: inflammation of the internal layers of eye (endophthalmitis), headache, closure of the retinal vein (retinal vascular occlusion), eye nerve disorder, increase in pigment of a circular area of macula (maculopathy), loss of portion of eye nerve disc fibre (optic atrophy), conjunctival ulcer, iris neovascularisation, retinal exudates, vitreous degeneration, vitreous detachment, posterior capsule opacification, iris adhesions, ocular hyperaemia, sclera thinning, removal of extruded implant from sclera, eye discharge, itching in the eye (eye pruritus). * Other: swollen hair follicles, changes in the color of skin, thinning or softening of skin, acne, pimples, rashes, itching, weight gain, puffiness of face, muscle weakness, headache and tiredness.

DRUG INTERACTION

* No studies evaluating the interaction of fluocinolone with other drugs have been performed. However, this does not mean that no interactions exist.  * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. 

MECHANISM OF ACTION

Fluocinolone belongs to a group of medicines called as steroids. It prevents the release of substances in the body that cause inflammation.

DOSAGE

Always follow the instructions of doctor regarding the dosage and duration  * As cream, gel or ointment: Apply thinly 1-2 times daily. * As intraocular implants: Initially 1 implant, containing 0.59 mg of fluocinolone, to be surgically implanted into the posterior segment of the affected eye.

DOs and DON'Ts

* Do not start or continue the fluocinolone:             - If you are allergic to it or to any other content in the medicine             - If you have any infection in and around your eye             - If you have glaucoma (increased pressure inside your eye)             - If you are less than 18 years of age * Inform your doctor before taking the medicine:             - If you have had herpes infection of the eye in the past             - If you are taking medicines used to thin the blood             - If you are pregnant or planning to become pregnant or breast-feeding * Do not drive or operate machinery after taking fluocinolone because it may cause temporary vision blurring.

CONTRA INDICATIONS

* Patients who are allergic to fluocinolone or to any content in the formulation * If you have any infection in your eyes or glaucoma * If you have viral diseases of the cornea and conjunctiva, including active epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, mycobacterial infections, and fungal diseases. * Children less than 18 years of age.

FAQ

Q. Is fluocinolone safe in pregnancy?Fluocinolone may cause harm to the fetus. Hence, it is not advisable to take it in pregnancy without consulting your doctor.Q. Is fluocinolone a steroid?Yes, fluocinolone is a steroid drug.Q. Is available or sold over the counter?No, fluocinolone is a prescription drug. It is not available or sold over the counter.Q. Is used for acne or psoriasis?Fluocinolone is used for skin infections, acne, psoriasis or eye infections.Q. Is fluocinolone safe for infants?No, fluocinolone is not safe to be used in children less than 18 years of age. Q. Is fluocinolone the same as fluocinonide?Fluocinolone and fluocinonide are two different drugs belonging to the same class. They are used for the same indications.Q. Can fluocinolone cause hair growth?Fluocinolone may cause hair growth at the site of application. If you experience any such symptoms, please consult your doctor.

FURTHER INFORMATION

* Summary of product characteristics. https://www.medicines.org.uk/emc/medicine/27636 * Patient information leaflet. https://www.medicines.org.uk/emc/PIL.27632.latest.pdf * British national formulary (BNF 2011). * Drugs.com http://www.drugs.com/dosage/fluocinolone-ophthalmic.html * Drugs.com http://www.drugs.com/mtm/fluocinolone-topical.html

SUBSTITUTES

No substitutes found

INTERACTIONS

Can I take Lumacip Plus Cream(15gm) during pregnancy?

The drug should not be used by pregnant women. Experiences of drug use and evidence from studies in pregnant women have shown high risk to fetus. The risk of drug use in pregnant women outweighs the benefit.

Can I take Lumacip Plus Cream(15gm) while breastfeeding/lactation?

Contraindicated: The drug should not be used by breastfeeding women, as evidences from studies have shown that there is a high risk of causing significant damage to infants.

Can I take Lumacip Plus Cream(15gm) with alcohol?

No studies found