MRP:Rs. 75 for 1 Strip(s) (10 Capsule each)
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1

SALT INFORMATION

Alpha Lipoic Acid()

TYPICAL USAGE

Alpha lipoic acid (ALA) is used to enhance effects of primary antidiabetic therapy (adjuvant therapy) in patients with diabetes as it lowers blood glucose by binding to insulin (a hormone that controls blood sugar level in the body) receptor in the body which leads to increase glucose utilization. Also, due to its antioxidant activity, ALA is used to treat nerve damage due to uncontrolled blood sugar level that causes pain, tingling, or numbness over hands and feet (diabetic neuropathy).  ALA is used as an antioxidant as an adjuvant treatment of HIV, cancer, liver ailments, and various other conditions.

SIDE EFFECTS

* Allergic reactions (rashes, hives, itching), abdominal pain, urge to vomit (nausea), vomiting, loose motions (diarrhea), and sensation of spinning or rotation (vertigo)

DRUG INTERACTION

* Alpha lipoic acid supplementation can potentially increase the risk of hypoglycemia in patients with diabetes on insulin or oral antidiabetic agents  * Alpha lipoic acid at high concentrations may interact with biotin (vitamin B7).

MECHANISM OF ACTION

Alpha lipoic acid acts as a potent antioxidant (substance that protects against cell damage) by neutralizing the free radicals (waste products formed in the body during energy production) such as reactive oxygen and nitrogen species. Further, it initiates natural antioxidant processes in the body. It also maintains the levels of Vitamin E and Vitamin C in the body.

DOSAGE

* Always follow the instructions of doctor regarding the dosage and duration. * There are no established doses for alpha lipoic acid. * Oral:  * As an antioxidant support: 20 - 50 mg daily. * Diabetes and diabetic neuropathy: 800 mg daily in divided doses. * However, the dose may range from 300 mg to 1800 mg daily.

DOs and DON'Ts

* Food decreases the amount of alpha lipoic acid in the body; hence it should be taken on empty stomach about 1 hour before or 2 hours after consuming food. * Do not take alpha lipoic acid supplements on your own and as a sole treatment for diabetes, complications of diabetes and other conditions in which benefit may be claimed, as these diseases require proper medical treatment.

CONTRA INDICATIONS

* Alpha lipoic acid is not recommended for use in children.

FAQ

Q. Is alpha lipoic acid a vitamin?No, alpha lipoic acid is not a vitamin.Q. Is alpha lipoic acid an amino acid?No, alpha lipoic acid is not an amino acid.Q. Is alpha lipoic acid natural?Yes, alpha lipoic acid is natural as it is synthesized in the human body, and in a wide variety of foods from plant and animal sources Q. Is alpha lipoic acid same as lipoic acid?Yes, lipoic acid and alpha lipoic acid refer to the same molecule.Q. Is alpha lipoic acid good for weight loss?It is not yet studied or established in human beings whether ALA supplementation is beneficial for weigh loss.Q. Is alpha lipoic acid good for liver? It is not yet studied or established in human beings whether ALA supplementation is good for liver

FURTHER INFORMATION

* http://lpi.oregonstate.edu/infocenter/othernuts/la/ * http://umm.edu/health/medical/altmed/supplement/alphalipoic-acid * http://www.drugs.com/npp/alpha-lipoic-acid.html

Folic Acid()

TYPICAL USAGE

* Folic acid is used * For the treatment of: anemia due to folic acid deficiency caused by poor diet, poor absorption of food or increased requirement of folate in the body (as in pregnancy) * For prevention of: folate deficiency caused by some medicines and folate deficiency caused by long-term red blood cell damage or kidney dialysis

SIDE EFFECTS

* Rare: Allergic reaction (hypersensitivity) e.g. itchy or red skin, rash, swelling of the face, lips, tongue or throat or difficulty breathing or swallowing, shock (cold sweaty skin, weak pulse, dry mouth, dilated pupils), loss of appetite, feeling sick, a bloated feeling, wind

DRUG INTERACTION

* Folic acid may interacts with, antiepileptics to treat epilepsy and fits (e.g. phenytoin, phenobarbital and primidone), antibacterials to treat infections (e.g. chloramphenicol and co-trimoxazole), medicines to treat Crohn’s disease (disease affecting the bowel causing repeated abdominal cramps, diarrhea and blood in stools), rheumatoid arthritis (pain, swelling and deformity of the small joints of hands and feet) or cancer (e.g. methotrexate) * Medicines to treat diseases affecting the bowel causing repeated abdominal cramps, diarrhea and blood in stools (Ulcerative colitis, Crohn’s disease) or rheumatoid arthritis (pain, swelling and deformity of the small joints of hands and feet) (e.g. sulfasalazine) can reduce the absorption of folic acid * Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

* Folic acid is a component of the B group of vitamins and is necessary for the normal production and maturation of red blood cells.

DOSAGE

* Always follow the instructions of doctor regarding the dosage and duration * Tablet: * Adults (including the elderly):  5 mg a day for 4 months (maximum dose: 15 mg a day) * Children:  Children 1-18 years old: 5 mg a day for 4 months. (maintenance dose: 5 mg every 1-7 days)

DOs and DON'Ts

* Do not take folic acid if you are allergic (hypersensitive) to folic acid or any of the other ingredients * Talk to your doctoriIf you are pregnant , planning to become pregnant or are breastfeeding

CONTRA INDICATIONS

* Do not take folic acid * If you are allergic (hypersensitive) to folic acid or any of the other ingredients in the tablets or liquid * If you have a tumor or cancer * Patients with folate dependent tumors * Patients who have shown previous intolerance to the drug * Patients with an untreated vitamin B12 deficiency such as in certain anemia (e.g. pernicious anemia) and lifelong vegetarians * Patients with rare hereditary problems of intolerance to certain sugars like galactose, lactase deficiency or glucose–galactose malabsorption

FAQ

Q. Does folic acid contain iron? / can I take folic acid with iron supplement?Folic acid is a component of the B group of vitamins. It does not contain iron and can be taken with iron supplement.Q. Does vitamin D have folic acid?Folic acid is a component of the B group of vitamins and it does not have Vitamin D.Q. Is folic acid good for everyone/skin/health/polycystic ovarian syndrome (PCOS)/hair loss/anemia?Everyone needs folic acid for good health. It is good for skin, hair, polycystic ovarian syndrome (PCOS) and anemia. However, patients should follow the advice of the doctor regarding the use of folic acid.Q. Is folic acid necessary before pregnancy? Can I take folic acid without being pregnant?Folic acid is usually indicated in the treatment of megaloblastic anemia of pregnancy caused by poor diet, poor absorption of food or when requirements of folic acid are markedly increased during pregnancy and deficiency can lead to neural tube defects in babies (spina bifida). In addition folic acid is also used for prevention of folate deficiency caused by some medicines (e.g. phenytoin, phenobarbital and primidone used to treat epilepsy), folate deficiency caused by long-term red blood cell damage or kidney dialysis However, patients should follow the advice of the doctor regarding the use of folic acid.Q. Is Folvite safe during pregnancy?Folvite is trade name for active drug folic acid. Folic acid is safe for use in pregnancy. However, patients should follow the advice of the doctor regarding the dose and duration of use of folic acid.Q. Can I take folic acid during period/ovulation/in-vitro fertilization (IVF)?Folic acid has no known effect on periods and ovulation. It may be prescribed by your doctor during in-vitro fertilization, as it is usually indicated in the treatment of megaloblastic anemia of pregnancy.Q. Can I take folic acid during breastfeeding/ lactation?Folic Acid is excreted in the milk of lactating mothers; During lactation, folic acid requirements are markedly increased; however, amounts present in human milk are is adequate to fulfill infant requirements. Supplementation may be needed in low-birth-weight infants, in those who are breast-fed by mothers with folic acid deficiency or in those with infections of prolonged diarrhea.Q. Does folic acid delay periods/increase chances of getting pregnant/conception?Folic acid has no known effect on delaying periods or increasing chances of conception.Q. What is Folvite/ Fol123/ Folvite MB tablet used for?Folvite/ Fol123/ Folvite MB are the trade names for active drug folic acid. Folvite contains only folic acid which is a component of the B group of vitamins. While Fol123/ Folvite MB, in addition to folic acid also has other forms of vitamin B.Folic acid is usually indicated in the treatment of megaloblastic anemia of pregnancy caused by poor diet, poor absorption of food, or when requirements of folic acid are markedly increased during pregnancy, and deficiency can lead to neural tube defects in babies (spina bifida). In addition folic acid is also used for prevention of folate deficiency caused by some medicines (e.g. phenytoin, phenobarbital and primidone used to treat epilepsy), folate deficiency caused by long-term red blood cell damage or kidney dialysis However, patients should follow the advice of the doctor regarding the dose and duration of use of folic acid.Q. How long can I take folic acid for? Can I take folic acid for a year?Always follow the instructions of doctor regarding the dosage and durationQ. Does folic acid have side effects increase weight/acidity?Folic acid may have rare side effect like acidity, while it has no known effect on weight gain.Q. Can I take folic acid with milk?Folic acid has no known interactions with milk.Q. Can I take folic acid with birth control?Folic acid supplementation does not affect birth control, and can be taken if you are suffering from anemia due to folic acid deficiency However, always follow the advice of the doctor regarding the dose and duration of use of folic acid.Q. Can I take folic acid with Clomid (clomiphene-a non-steroidal fertility medicine)?Folic acid can be taken with Clomid. As it is usually indicated in the treatment of megaloblastic anemia of pregnancy caused by poor diet, poor absorption of food, or when requirements of folic acid are markedly increased during pregnancy, and where deficiency can cause neural tube defects in babies (spina bifida). In addition folic acid is also used for prevention of folate deficiency caused by some medicines (e.g. phenytoin, phenobarbital and primidone used to treat epilepsy); folate deficiency caused by long-term red blood cell damage or kidney dialysis However, patients should follow the advice of the doctor regarding the dose and duration of use of folic acid.Q. Can I take folic acid with methotrexate/warfarin/calcium/metformin/antibiotics?Folic acid may interact with medicines such as methotrexate/sulfonamide antibiotics (sulfasalazine, cotrimoxazole etc). It has no known effect if taken with warfarin/calcium/metformin.Q. Can I take folic acid with multivitamin/pregnacare (vitamin supplement)/prenatal vitamins (Prenatal vitamins are vitamin and mineral supplements intended to be taken before and during pregnancy and during postnatal lactation)?Folic acid can be taken with multivitamin/pregnacare/prenatal vitamins

FURTHER INFORMATION

* Patient information leaflet. * https://www.medicines.org.uk/emc/PIL.10543.latest.pdf * https://www.medicines.org.uk/emc/PIL.18084.latest.pdf * Summary of product characteristics. * https://www.medicines.org.uk/emc/medicine/10658

Elemental Zinc()

TYPICAL USAGE

Zinc is used for treatment and prevention of zinc deficiency and its consequences, including stunted growth and acute diarrhea in children, and slow wound healing. It is also used for boosting the immune system, treating the common cold and recurrent ear infections, and preventing lower respiratory infections. It is also used for malaria and other diseases caused by parasites. Zinc is also used for an eye disease called macular degeneration, for night blindness, and for cataracts. It is also used for asthma; diabetes; high blood pressure; acquired immunodeficiency syndrome (AIDS); and skin conditions such as psoriasis, eczema, and acne.

SIDE EFFECTS

Taking high amounts of zinc is likely unsafe. High doses above the recommended amounts might cause fever, coughing, stomach pain, fatigue, and many other problems.

DRUG INTERACTION

Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval.

MECHANISM OF ACTION

Zinc is needed for the proper growth and maintenance of the human body. It is found in several systems and biological reactions, and it is needed for immune function, wound healing, blood clotting, thyroid function. Zinc plays a key role in maintaining vision, and it is present in high concentrations in the eye. Zinc deficiency can alter vision, and severe deficiency can cause changes in the retina (the back of the eye where an image is focused).

CONTRA INDICATIONS

NA

Vitamin B6()

TYPICAL USAGE

It is used for the treatment and prevention of vitamin B6 deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.

SIDE EFFECTS

Nausea, stomach upset, headache, sleepiness, tingling, prickling, burning or sensation of tightness.

DRUG INTERACTION

Pyridoxine is known to interact with other drugs like ethionamide, fosphenytoin, isoniazid, levodopa, nitrofurantoin, penicillamine, phenobarbitone, phenytoin (Na). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).

CONTRA INDICATIONS

Hypersensitivity.

Methylcobalamin()

TYPICAL USAGE

* Methylcobalamin is an active form of vitamin B12, which is used to treat anemia as well as nerve damage with numbness, tingling, pain in various neurological disorders.

SIDE EFFECTS

* Generally Methylcobalamin is well tolerated. However, a few side effects like gastrointestinal discomfort (including loss of apetitte, urge to vomit or loose motions) and rash may be seen after administration.

DRUG INTERACTION

* Methylcobalamin may interact with metformin, H2 receptor antagonists (cimetidine, ranitidine etc), antibiotics (chloramphenicol, neomycin, aminosalicylic acid and aminoglycosides group e.g. gentamicin), colchicine, phenobarbitol. These drugs may alter the effects of each other. * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

* Methylcobalamin plays a key role in recovery process of damaged nerve cells and also it maintainins proper function of nerve cells.

DOSAGE

        Always follow the instructions of doctor regarding the dosage and duration. * Peripheral neuropathies in adult: 1500 mcg/day in 3 divided doses.

DOs and DON'Ts

* Do not take methylcobalmin if you are allergic (hypersensitive) to methylcobalamin, or any of the other ingredients of this medicine. * Tell your doctor if your occupation requireds you to handle mercury or its compound. * Do not use methylcobalamin over a period of months, if there is a lack of satisfactory clinical response.

CONTRA INDICATIONS

* Methylcobalamin should not be  taken by patients who are allergic (hypersensitive) to methylcobalamin, or any of the other ingredients of this medicine.

FAQ

Q. What is methylcobalamin/ mecobalamin/Neurokind/ Nurokind OD?Methylcobalamin (mecobalamin/Neurokind/ Nurokind OD) is an active form of vitamin B12. It is water soluble and orally absorbed. It  is found in animal-based foods and in supplement form.Q. Is methylcobalamin safe in pregnancy?Methylcobalamin is not recommended in pregnancy. Patients should follow the advice of the doctor regarding its use.Q. Is methylcobalamin the same as cyanocobalamin?No. Cyanocobalamin is different form of vitamin B12.Q. What is Nurokind G, Nurokind plus, Nurokind Next, Nurokind LC, Nurokind Gold?Nurokind G contains methylcobalmine and gabapentin. Nurokind plus contains methylcobalamin, folic acid, vitamin B1, vitamin B6 and alfa lipoic Acid. Nurokind Next contains methlcobalamin, alphalipoic acid, benfotiamine, pyridoxine hydrochloride, biotin, folic acid, chromium. NurokindL C contains L-carnitine, L-tartrate, methylcobalamin, folic acid. Nurokind Gold contains ginseng extract, mixed carotene 10%, niacinamide, vitamin B6, methylcobalamin, vitamin D3, refined wheat germ oil, folic acid, elemental calcium, elemental phosphorus, ferrous fumarate, zinc sulphate monohydrate, elemental magnesium, elemental manganese, elemental copper, elemental iodine, elementalpotassium.

FURTHER INFORMATION

* Prescribing information: www.aci-bd.com/Brand/Phyton.pdf * Patient information leaflet. portal.bpfk.gov.my/view_file.cfm?fileid=1476

SUBSTITUTES

No substitutes found

INTERACTIONS

Can I take Mbclo Plus Cap during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Mbclo Plus Cap while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Mbclo Plus Cap with alcohol?

No studies found