Neurobion Forte

Tablet
MRP:Rs. 6.96 for 1 Strip(s) (10 Tablet each)
Discounted Price:Rs. 6.96 (0% OFF)
1

SALT INFORMATION

Pyridoxine(3 mg)

TYPICAL USAGE

Pyridoxine is used to treat dysfunction of nerves due to isoniazid (anti-tuberculosis drug), idiopathic sideroblastic anemia (abnormal blood cells produced by bone marrow) and Vitamin B6 deficiency states.

SIDE EFFECTS

Long term administration of large doses is associated with the development of severe peripheral neuritis resulting in numbness and pain, usually in hands and feet.

DRUG INTERACTION

Pyridoxine may interact with other drugs like isoniazid, penicillamine, oral contraceptives, and levodopa. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Pyridoxine, a vitamin B6 supplement is required for the proper function of glucose, fats, and proteins in the body. It is also required for the growth and development of the brain, nerves, skin, and many other parts of the body.

Thiamine Mononitrate(10 mg)

TYPICAL USAGE

Lung cancer and pancreatic cancer, mild chronic deficiency, severe deficiency, thiamine deficiency prophylaxis, thiamine deficiency treatment.

SIDE EFFECTS

Nausea, urticaria, Gi bleeding, angioneurotic edema, restlessness, pruritis, pulmonary edema, hemorrhage, cyanosis,

DRUG INTERACTION

Thiamine is known to interact with other drugs like aluminium hydroxide and oxide, amiloride (HCl), bumetanide, chlorthalidone, estradiol (Valerate), estrogens conjugated, fluorouracil, magnesium carbonate, magnesium oxides and hydroxides, metformin (HCl), phenobarbital Sodium, phenobarbitone, triamterene, vecuronium (Br). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Thiamine is mainly the transport form of the vitamin, while the active forms are phosphorylated thiamine derivatives. There are five known natural thiamine phosphate derivatives: thiamine monophosphate (ThMP), thiamine diphosphate (ThDP), also sometimes called thiamine pyrophosphate (TPP), thiamine triphosphate (ThTP), and the recently discovered adenosine thiamine triphosphate (AThTP), and adenosine thiamine diphosphate. Each derivative has unique functions, however, most are involved as coenzymes.

Riboflavin(10 mg)

TYPICAL USAGE

Arabinoflavinosis, Vitamin deficiency.

SIDE EFFECTS

Discoloration of urine, Swelling of face, Difficulty breathing, Swelling of lips and tongue.

DRUG INTERACTION

Arabinoflavinosis, Vitamin deficiency.

MECHANISM OF ACTION

Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of the antioxidant reduced glutathione. Reduced glutathione is the cofactor of the selenium-containing glutathione peroxidases among other things. The glutathione peroxidases are major antioxidant enzymes. Reduced glutathione is generated by the FAD-containing enzyme glutathione reductase.

Cyanocobalamin(15 mcg)

TYPICAL USAGE

Addisonian pernicious anaemia, Congenital cobalamine malabsorption, Congenital intrinsic factor deficiency, Homocystenemia, Ileal resection, Methylmalonylacidurias, Nutrition deficiency, Post gastrectomy vit B-12 deficiency, Transcobalamin II deficiency, and can also be given in adjunctive therapy as an alternative drug of choice in Vitamin-B12 defeciency of dietary origin.

SIDE EFFECTS

Hypersensitivity reactions, Shivering, Dyspnea, Persistant urticaria, Bronchospasm.

DRUG INTERACTION

Cyanocobalamin is known to interact with other drugs like Alcohol, Chloramphenicol, Cholestyramine, Colchicine, Colchicine, Epoetin, Glucose, Neomycin, Neomycin, Omeprazole.

MECHANISM OF ACTION

Vitamin B12 is used in the body in two forms: Methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells.

Nicotinamide(45 mg)

TYPICAL USAGE

To treat inflammatory skin disease like acne, anxiety and Alzheimer’s disease

SIDE EFFECTS

Hepatotoxicity, cholestasis, portal fibrosis, headache, fatigue, urge to vomit (nausea), stomach upset, dizziness, dry hair, diarrhea, blurred vision, flushing and rash.

DRUG INTERACTION

Nicotinamide is known to interact with other drugs like carbamazepine, primidone by reducing its clearance. It also interacts with drugs like chloramphenicol, phenytoin, methotrexate, penicillamine, other vitamins/nutritional supplements, antibiotics like ciprofloxacin, levofloxacin and tetracyclines. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Nicotinamide is a component of two coenzymes, which bring about tissue respiration, lipid, amino acid, protein, and purine metabolism. Nicotinamide lowers blood cholesterol and triglyceride levels by inhibiting the synthesis of very low density lipoproteins.

SUBSTITUTES

No substitutes found

INTERACTIONS

Can I take Neurobion Forte during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Neurobion Forte while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Neurobion Forte with alcohol?

No studies found