SALT INFORMATIONEplerenone(25 mg)
Eplerenone is used to treat hypertension (high blood pressure). It is also used to treat post myocardial infarction and congestive heart failure (inefficient working of heart).
Angioneurotic edema, albuminuria, vaginal bleeding, gynecomastia, myocardial infarction, anaphylactic reactions, shortness of breath, dizziness, nausea, vomiting, diarrhea, hypotension, cough, light headedness.
Eplerenone is known to interact with other drugs like aspirin, diazoxide, enalapril (Maleate), erythromycin, ketoconazole, lithium. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Eplerenone binds to the mineralocorticoid receptor and thereby blocks the binding of aldosterone (component of the renin-angiotensin-aldosterone-system, or RAAS). Aldosterone synthesis, which occurs primarily in the adrenal gland, is modulated by multiple factors, including angiotensin II and non-RAAS mediators such as adrenocorticotropic hormone (ACTH) and potassium. Aldosterone binds to mineralocorticoid receptors in both epithelial (e.g., kidney) and nonepithelial (e.g., heart, blood vessels, and brain) tissues and increases blood pressure through induction of sodium reabsorption
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Can I take Planep (25mg) during pregnancy?
Studies in animals have shown no risk to the fetus, however there are no sufficient studies in humans. Patients should follow the advice of the doctor regarding its use. Patients should follow the advice of the doctor regarding its use.