Levosulpiride is used in the treatment of psychosis, depression, frequent persistent heart burn, gastro-oesophageal reflux disease, irritable bowel syndrome, indigestion (dyspepsia).
Absence of menstruation (amenorrhea), abnormally large breast in males (gynecomastia), abnormal milk secretion (galactorrhoea), changes in sexual desire (libido), neuroleptic malignant syndrome (a rare side effect characterized by fever, muscular rigidity, altered mental status)
* Effectiveness is altered with concomitant intake sucralfate, aluminium- and magnesium-containing antacids. * Effect on GI motility may be antagonised by anticholinergic agents, narcotics and analgesics. * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Levosulpride belongs to a class of medications called atypical antipsychotic agent. It acts by inhibiting the receptor (D2 and D3) found in the brain and subsequently decreasing the level of chemical compound (dopamine) present in the brain.
Always follow the instructions of doctor regarding the dosage and duration. * Gastro-oesophageal reflux disease, irritable bowel syndrome, dyspepsia in adults: 25 mg three times a day.
DOs and DON'Ts
* Do not take thiss drug if you are allergic to levosulpride * Befor taking the drug consult your doctor if you are pregnant, planning to become pregnant or breast feding * Immediately consult your doctor if you have absence if periods, abnormal milk secretion or changes in sexual desire, fever, muscle stiffness. * The drug can make you dizzy. Be careful when driving vehicles or operating machines.
* Patients with allergy to levosulpiride or any of its ingredients * Patients who have pheochromocytoma, fits( epilepsy), manic states, hyperprolactinaemia, mammary dysplasia, malignant mastopathies, cardiac impairment gastrointestinal bleeding, mechanical obstruction or perforation.
Q.Is levosulpiride safe?Levosulpiride is safe if used at prescribed doses for the prescribed duration as advised by your doctor.Q.Is levosulpiride an antidepressant?No, it is used in the treatment of gastro-oesophageal reflux disease, irritable bowel syndrome, psychosis, dyspepsia.Q.What is levosulpiride? What are its uses?Levosulpiride belong to class of medication called as atypical antipsychotics. It acts by decreasing the activity of dopamine in the brain. Levosulpiride is used in the treatment psychosis, depression, gastro-oesophageal reflux disease, irritable bowel syndrome and dyspepsiaQ.Does levosulpiride cause erectile dysfunction?No. patients should follow advice of the doctor regarding the possible side effects.
1.Drug bank information. http://www.drugbank.ca/drugs/DB003912.Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th ed. New York, NY: McGraw-Hill; 2011
Rabeprazole is used to treat symptoms of gastric acidity, gastro-intestinal reflux disease (heart burn), stomach and intestinal ulcers, and diseases associated with excessive acid production (Zollinger Ellison Syndrome).
* Common: sore throat, nose infection, flu like symptoms, urge to vomit, vomiting, diarrhea, constipation, gas, abdominal pain, back pain, non-specific pain, weakness, sleeplessness, headache, dizziness. * Uncommon: nervousness, inflammation of the sinuses, chest pain, dry mouth, indigestion, belching, rash, muscle pains, joint pains, fracture of the hip, wrist or spine, leg cramps, urinary tract infection, chills, fever, liver toxicity.
* Drugs like atazanavir, ketaconazole or itraconazole may alter effect of rabeprazole or vice versa. * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Rabeprazole belongs to class of medications called proton pump inhibitors. It blocks the activity of the proton pumps in the stomach wall that produce acid, thereby reducing the amount of acid produced in the stomach.
Always follow the instructions of doctor regarding the dosage and duration * Heart burn (gastro-esophageal reflux disease): 20 mg of once daily for 4 to 8 weeks. * Zollinger-Ellison Syndrome: 60 mg once a day. * Eradication of Helicobacter pylori infection: 20 mg to be taken twice each day and normally for 7 days. Can also be used with other antibiotics for treatment of H. pylori infection.
DOs and DON'Ts
* Take rabeprazole tablet an hour before a meal * Do not take rabeprazole if you are allergic (hypersensitive) to rabeprazole or other PPI'S (pantoprazole, omeprazole, ) * If you have to the drug for a very long time, take calcium and Vitamin D supplemets to prevent risk of fractures * Consult your doctor before taking this drug if you are pregnant or breast feeding
* Children or patients who are allergic (hypersensitive) to rabeprazole or any of the other ingredients. * Patients who are taking atazanavir.
Q. Is rabeprazole/ Rabicip-20/ Rabium 20 mg/ Rabium DSR/ Veloz 20/ Veloz D/ Rablet 20/ Rablet D/ Rekool D an over the counter?Rabeprazole (also available as / Rabicip-20/ Rabium 20 mg/ Rabium DSR/ Veloz 20/ Veloz D/ Rablet 20/ Rablet D/ Rekool D) although available over the counter, it should be taken only on doctor’s advice.Q. Is rabeprazole safe during pregnancy?No. Patients should follow the advice of the doctor regarding its use.Q. Is rabeprazole an antacid / antibiotic?Rabeprazole is a proton pump inhibitor which suppresses acid production in stomach. It is not antacid which reacts and neutralizes acid. It is not an antibiotic as it does not kill bacteria.Q. Does rabeprazole cause osteoporosis/ insomnia?Rabeprazole may cause osteoporosis/ insomnia. Please consult your doctor if you experience such side effect.Q. Can i take gaviscon with rabeprazole?Depending upon individual’s response, there should be an interval of at least 2 hours between the two drug administrations.
1. Summary of product characteristics: https://www.medicines.org.uk/emc/medicine/2577#POSOLOGY2. Patient information leaflet. https://www.medicines.org.uk/emc/PIL.27145.latest.pdf
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