SALT INFORMATIONRosuvastatin(5 mg)
Rosuvastatin is used for the treatment and prevention of high cholesterol (hypercholesterolemia), high lipid levels (hyperlipidemia), and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, and disease of coronary artery of heart (coronary heart disease).
* Common: stomach pain, constipation, feeling sick, muscle pain, weakness, dizziness, abdominal pain, an increase in the amount of protein in the urine, diabetes (if you have high levels of sugars and blood pressure). * Uncommon: Rash, itching or other skin reactions.
* Rosuvastatin is known to interact with drugs such as Cyclosporin, warfarin or clopidogrel, fibrates (such as gemfibrozil, fenofibrate) or any other medicine used to lower cholesterol (such as ezetimibe), indigestion remedies, erythromycin, fusidic acid (an antibiotic), an oral contraceptive (the pill), hormone replacement therapy or ritonavir with lopinavir and/or atazanavir. The effects of these medicines could be altered by rosuvastatin or they could alter the effects of rosuvastatin. * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
MECHANISM OF ACTION
Rosuvastatin belongs to a group of medications called statins (lipid-lowering agents) or HMG CoA reductase inhibitors. It acts by blocking the enzyme HMG CoA reductase and formation of cholesterol, thus, lowering the blood lipid levels.
* Always follow the instructions of doctor regarding the dosage and duration. * Adults: 5-40 mg once daily. * Children with heterozygous familial hypercholesterolemia (10 to 17 years of age): 5-20 mg/day.
DOs and DON'Ts
* Do not take antacids for atleast 2 hours before and after taking this drug * Consult your doctor if you develop sudden muscle pain, fever or weakness * Consult your doctor if you notice dark urine or yellowing of eyes or skin * Do not take rosuvastatin if you are allergic (hypersensitive) to rosuvastatin or any of the other ingredients of rosuvastatin. * Do not take this drug if if you are pregnant or breast-feeding. * If you become pregnant while taking rosuvastatin stop taking it immediately and tell your doctor.
* Children younger than 6 years. * Higher dose (40 mg) is not suitable for use in children and adolescents below 18 years of age. * If you have severe respiratory failure.
Q. Is rosuvastatin/ Crestor/ Crevast F10/ Novastat TG available in in the United States?Yes. It is available in United States with the name “Crestor”.Q. Is rosuvastatin lipophilic?No. It is hydrophilic in nature.Q. Is rosuvastatin safe?Rosuvastatin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.Q. Is rosuvastatin gluten free?Please refer to package insert of the prescribed brand for gluten related information.Q. Is rosuvastatin better than simvastatin?Rosuvastatin and simvastatin belong to same class of medication called as HMG CoA reductase inhibitor (or statins) with similar action but their effect may vary upon individual response.
1. Prescribing information. http://www.astrazeneca-us.com/cgi-bin/az_pi.cgi?product=crestor&country=us&popup=no2. Patient information leaflet. https://www.medicines.org.uk/emc/medicine/119723. Medlineplus: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a603033.html
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