SALT INFORMATIONBupivacaine(5 mg)
Percutaneous infiltration anaesthesia, Peripheral nerve block, Sympathetic nerve block, Retrobulbar block, Caudal block and Lumbar epidural block.
CNS excitation may be followed by depression. Hypotension, bradycardia, arrhythmias and cardiac arrest; methaemoglobinaemia; seizures, restlessness, dizziness. Hypersensitivity. Prolonged block, Cardiac and sudden respiratory arrest.
Decreased duration with hyaluronidase. Decreased clearance with cimetidine and ranitidine. Potentiates lidocaine and mepivacaine. Allergic-type reactions with formulations containing sodium metabisulfite. May potentiate systemic toxicity of other local amide anaesthetics. Increased risk of myocardial depression with antiarrhythmics.
MECHANISM OF ACTION
Bupivacaine blocks both the initiation and conduction of nerve impulses reducing the permeability of neuronal membranes to Na ions resulting in inhibition of depolarization with resultant blockade of conduct.
- Sensorcaine (100mg)(20 ml Powder for Injection in Vial)Astra ZenecaRs. 71.30/Powder for InjectionRs. 71.30save 87% more per Powder for Injection
- Sensorcaine 0.5%(20ml)(1 Powder for Injection in Vial)Astra ZenecaRs. 78/Powder for InjectionRs. 78pay 186% more per Powder for Injection
- Sensorcaine Heavy(0.5)(2 ml Powder for Injection in Vial)Astra ZenecaRs. 240.60/Powder for InjectionRs. 240.60pay 341% more per Powder for Injection
- Sensorcaine Heavy(20mg)(4 mg Powder for Injection in Vial)Astra ZenecaRs. 258.50/Powder for InjectionRs. 258.50pay 137% more per Powder for Injection
Can I take Sensorcaine Heavy(0.5) during pregnancy?
Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.