MRP:Rs. 60 for 1 Tube(s) (30 g Cream each)
Discounted Price:Rs. 60 (0% OFF)
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Composition

Clobetasole Propionate(0.05%W/W)

SALT INFORMATION

Clobetasole Propionate(0.05%W/W)

TYPICAL USAGE

Skin Infection

SIDE EFFECTS

Headache, Fatigue, Nausea, Constipation, Dry mouth, Sedation, Skin rash, Gastralgia.

DRUG INTERACTION

If overdose is suspected, contact your physician.

MECHANISM OF ACTION

The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. Initially, however, clobetasol, like other corticosteroids, bind to the glucocorticoid receptor, which complexes, enteres the cell nucleus and modifies genetic transcription (transrepression/transactivation).

SUBSTITUTES

25 Substitutes
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  • Powercort Skin(15gm)
    (15 g Cream in Packet)
    Glenmark Pharmaceuticals Ltd
    Rs. 11.13/Cream
    Cream
    Rs. 11.13
    save 63% more per Cream
  • Betanate Skin(10gm)
    (10 g Cream in Tube)
    Cfl Pharmaceuticals Ltd (Cosme Healthcare)
    Rs. 22.50/Cream
    Cream
    Rs. 22.50
    pay 12% more per Cream
  • Closol Skin(15gm)
    (15 g Cream in Tube)
    Sapient Laboratories Pvt Ltd
    Rs. 28.90/Cream
    Cream
    Rs. 28.90
    save 4% more per Cream
  • Psorobet Skin(15gm)
    (15 g Cream in Tube)
    Bombay Tablet Mfg Co Pvt Ltd
    Rs. 31.95/Cream
    Cream
    Rs. 31.95
    pay 7% more per Cream
  • Excel Skin(15gm)
    (15 g Cream in Tube)
    Ranbaxy Laboratories Ltd
    Rs. 32.80/Cream
    Cream
    Rs. 32.80
    pay 9% more per Cream

INTERACTIONS

Can I take Topinate Skin(30gm) during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Topinate Skin(30gm) while breastfeeding/lactation?

Possibly unsafe: Evidence from studies in breastfeeding women show that there is a definite risk of side effects to the breastfed infants. However, use of the drug in breastfeeding women is acceptable in spite of the risk to the infants, if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective. Patients should follow the advice of the doctor regarding its use.

Can I take Topinate Skin(30gm) with alcohol?

No studies found