Triclor (500mg)

Capsule
MRP:Rs. 44 for 1 Strip(s) (10 Capsule each)
Discounted Price:Rs. 44 (0% OFF)
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Composition

Chloramphenicol(500 mg)

SALT INFORMATION

Chloramphenicol(500 mg)

TYPICAL USAGE

Enteric fever (Typhoid and Para typhoid).H.Influenzae meningitis. Anaerobic infections, intraocular infections, urinary tract infections, conjunctivitis, external ear infections.Corneal ulcer, bacterial conjunctivitis, trachoma, ocular infections.Otitis externa, chronic otitis media. Pre and post antral or mastoid surgery.

SIDE EFFECTS

Encephalopathy, pseudomembranous colitis, anemia, urticaria, anemia, thrombocytopenia, hepatitis, ototoxicity, peripheral neuropathy, optic neuritis, hemolytic reactions, interstitial nephritis, headache, nausea, vomiting, maculopapular rash, stomatitis, confusion, pruritus, depression, glossitis, delirium, transient stinging.

DRUG INTERACTION

Chloramphenicol is known to interact with other drugs like amoxicillin, ampicillin, ascorbic acid, azlocillin (Na), bacampicillin, benzathine penicillin, carbenicillin (Na), chlorpropamide, chymotrypsin, cimetidine (HCl), ciprofloxacin, cloxacillin, clozapine, colistin (Sulphate & Sulphomethate Na), cyanocobalamin, cyclophosphamide, dicloxacillin (Na), ethinyloestradiol, floxacillin (Na), fosphenytoin, estodene, glibornuride, gliquidone, hydroxocobalamin, ichthammol, iron dextran, iron salts, iron sorbitol, mecillinam, mecobalamin, nafcillin, oxacillin, paracetamol, phenobarbitone, phenytoin (Na), piperacillin (Na),pivmecillinam (HCl), primidone, procaine penicillin, promethazine (HCl),rifampicin, sulfapyridine, tolbutamide, warfarin (Na).

MECHANISM OF ACTION

Chloramphenicol is lipid-soluble, allowing it to diffuse through the bacterial cell membrane. It then reversibly binds to the L16 protein of the 50S subunit of bacterial ribosomes, where transfer of amino acids to growing peptide chains is prevented (perhaps by suppression of peptidyl transferase activity), thus inhibiting peptide bond formation and subsequent protein synthesis.

SUBSTITUTES

44 Substitutes
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  • Tycol (500mg)
    (10 Capsule in Strip)
    Zydus Cadila
    Rs. 4.07/Capsule
    Capsule
    Rs. 40.70
    save 7% more per Capsule
  • Chloramphenicol (500mg)
    (100 Capsule in Strip)
    Acichem Laboratories
    Rs. 2/Capsule
    Capsule
    Rs. 200
    save 55% more per Capsule
  • Chloraxin (500mg)
    (6 Capsule in Strip)
    Cipla Ltd
    Rs. 6.13/Capsule
    Capsule
    Rs. 36.75
    pay 39% more per Capsule
  • Starphenicol (500mg)
    (10 Capsule in Strip)
    Cadila Pharmaceuticals Ltd
    Rs. 6.13/Capsule
    Capsule
    Rs. 61.25
    pay 39% more per Capsule
  • Paraxin (500mg)
    (1 Capsule in Strip)
    Abbott India Ltd
    Rs. 6.35/Capsule
    Capsule
    Rs. 63.50
    pay 1343% more per Capsule

INTERACTIONS

Can I take Triclor (500mg) during pregnancy?

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

Can I take Triclor (500mg) while breastfeeding/lactation?

Contraindicated: The drug should not be used by breastfeeding women, as evidences from studies have shown that there is a high risk of causing significant damage to infants.

Can I take Triclor (500mg) with alcohol?

No studies found