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Composition

Progesterone(100 mg)

SALT INFORMATION

Progesterone(100 mg)

TYPICAL USAGE

Progesterone is used to prevent recurrent miscarriage and maintain pregnancy; to treat absence of menstruation (amenorrhoea) in women of childbearing age and abnormal uterine bleeding; as a hormone replacement therapy in post-menopausal women; to treat premenstrual syndrome (feelings of tension, irritability, depression, headache, breast tenderness, weight gain and bloating that occurs 7-10 days before menstruation) and depression following child birth. 

SIDE EFFECTS

Urge to vomit (nausea), vomiting, diarrhea, pain in abdomen and lower abdomen, excessive gas in stomach; weight gain; fluid retention leading to swelling; tiredness; tenderness in breast; irritability, mood swings, temporary feeling of sleepiness and dizziness following intake of progesterone; menstrual abnormalities (absent menstruation, bleeding/spotting in between menstrual periods, increased or decreased menstrual flow), abnormal vaginal discharge; breathlessness, skin rashes and itching.

DRUG INTERACTION

* Taking progesterone with conjugated estrogen may decrease the level of estradiol. * Drugs like carbamazepine, phenytoin, and rifampicin may interfere with the activity of progesterone when taken orally.  * Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION

Progesterone belongs to a class of medications called progestins (female hormones). It is used as a part of hormone replacement therapy to bring on the menstruation by decreasing the levels of estrogen in the uterus and replacing the natural progesterone in women who are lacking.

DOSAGE

Always follow the instructions of doctor regarding the dosage and duration. * Adults          - Hormonal replacement therapy in menopause women: 200 mg tablet daily as a single                 daily dose at night for 12-14 days of each month.          - Treatment of absence of menstruation (amenorrhea): 400 mg orally daily for 10 days          - Premenstrual syndrome: 200 mg tablet daily.

DOs and DON'Ts

* Progesterone should be taken on an empty stomach or at least one hour before food or two hours after food. * Do not take progesterone and consult your doctor:          - If you have ever had any unexpected and unexplained bleeding from your vagina which               was not due to your normal monthly period.          - If you have liver problems such as jaundice.          - If you have a history of breast cancer.          - If you have ever had stroke, heart attack or diseases associated with blood clots. * Consult your doctor if you are pregnant, think you may be pregnant or planning a family before taking progesterone. * Do not take progesterone without informing your doctor if you are breast-feeding. * Do not drive a motor vehicle or operate a machine immediately after taking progesterone. You may experience a temporary (1 to 3 hours) feeling of sleepiness and dizziness after taking progesterone.  * Oral progesterone should preferably be taken at bedtime. * Consult  your doctor about any severe stomach pain or yellowing of your eyes or skin. * Immediately consult your  if you have sudden vision changes or one-sided weakness (signs of stroke) or chest pain and trouble breathing (signs of a pulmonary embolism).

CONTRA INDICATIONS

* If you are allergic to progesterone or any other ingredients in the medicine. * Patients who have, had or suspected to have breast cancer. * Patients with undiagnosed vaginal bleeding, blood clot in veins (thrombophlebitis) or those who have severe liver damage. * patients who have or have a history of any disease related to blood clots (active deep vein thrombosis, pulmonary embolism).

FAQ

Q. Is progesterone a steroid?Progesterone is a steroidal hormone naturally produced by the body and essential for the maintenance of a healthy uterus.Q. Is progesterone injection painful?Progesterone injection is an oil-based preparation and may cause discomfort of varying degrees. Q. Is progesterone/susten/susten200/ utrogestan safe during pregnancy?Susten and utrogestan are trade names for hormone progesterone. Studies of progesterone in pregnant animals have shown no risk to the growing fetus; however, there are no sufficient studies in pregnant women. Please follow the advice of your doctor regarding use of progesterone during pregnancy for vaginal use.Q. Is progesterone necessary during pregnancy / to prevent miscarriage?Progesterone may be prescribed in certain cases of pregnancy to avoid risk of miscarriage. It is essential for the maintenance of a healthy uterus which in turn is favorable to support pregnancy.Q. Is progesterone necessary after IUI?You may be instructed to take progesterone after an intrauterine insemination (IUI) procedure to make the uterus more favorable for pregnancy.Q. Is estrogen and progesterone the same?No. Estrogen and progesterone are two different steroidal hormones that work together for the development and maintenance of the female reproductive system.Q. Is progesterone/utrogestan safe?Yes. Utrogestan is a trade name for hormone progesterone. Progesterone is safe if used at prescribed doses for the prescribed duration as advised by your doctor.Q. Is progesterone an androgen / diuretic / probiotic?No. Progesterone belongs to a class of medications called progestins (female hormones) and is different from androgens (predominantly male hormones).Q. Is utrogestan bioidentical/ natural progesterone / containing HCG?Yes. Utrogestan is a trade name for hormone progesterone. It is structurally and functionally identical to the progesterone hormone naturally produced by the body and therefore bioidentical. It is sometimes referred to as natural progesterone, although it is synthesized in laboratories. It does not contain human chorionic gonadotropin (HCG) hormone.Q. Is utrogestan the same as prometrium?Utrogestan and prometrium are trade names for hormone progesterone.Q. Is utrogestan same as cycloset?No. Utrogestan and cycloset contain different active drugs. Utrogestan is a trade name for hormone progesterone. Cycloset is a trade name for active drug bromocriptine.Q. Can I take progesterone during my period?Progesterone is prescribed to initiate and normalize periods and should be taken before your menstrual cycle. Please follow the advice of your doctor regarding use of progesterone. Q. Can I take progesterone during the day?Progesterone should be taken on an empty stomach or at least one hour before food or two hours after food preferably at bedtime. You may experience sleepiness and dizziness for few hours after taking progesterone.Q. Can I take progesterone with food?Progesterone should be taken on an empty stomach or at least one hour before food or two hours after food.Q. Does progesterone/susten/susten400/susten100/utrogestan delay or stop period?Susten and utrogestan are trade names for hormone progesterone. Progesterone can delay or stop periods for as long as it is taken. Your periods will return within a few days of stopping. Q. Does progesterone delay period after IVF?Progesterone is prescribed after in vitro fertilization (IVF) to make the uterus more favorable to pregnancy. You will not get your periods if you become pregnant after IVF or as long as you take progesterone. Your periods will return within a few days of stopping progesterone, if you are not pregnant. Q. Does utrogestan cause spotting?Utrogestan is a trade name for hormone progesterone. Bleeding/spotting in between menstrual periods is a common side effect of taking progesterone.Q. Does progesterone increase breast size / cause acne/ sleepiness?Progesterone has a side effect of causing breast tenderness, discomfort and increase in size. Acne is also a common side effect of taking progesterone. You may experience sleepiness and dizziness for few hours after taking progesteroneQ. Does progesterone prevent pregnancy?No. Progesterone is used a hormone replacement therapy. Synthetic progesterone alone in called ‘minipill’ is used to prevent pregnancy (for birth control).Q. Can I take progesterone without a uterus?Progesterone is not needed in women without a uterus or those who have undergone hysterectomy (surgery to remove the uterus).Q. Can I take progesterone with levothyroxine/synthroid/ tamoxifen/clomid?There are no known drug interactions between progesterone when taken with synthroid (active drug- levothyroxine) or tamoxifen or clomid (active drug- clomiphene). However, inform your doctor about all medications currently taken before starting and while on progesterone.Q. Can I just take progesterone without estrogen?Yes. Your doctor may prescribe medicines that contain only progesterone.

FURTHER INFORMATION

Patientinformation leaflet. https://www.medicines.org.uk/emc/PIL.15059.latest.pdf <>2.      Summary of product characteristics.https://www.medicines.org.uk/emc/medicine/15056 <>Prescribinginformation.http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019781s013lbl.pdf <>

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INTERACTIONS

Can I take Urovin (100mg) during pregnancy?

Studies in animals have shown no risk to the fetus, however there are no sufficient studies in humans. Patients should follow the advice of the doctor regarding its use. Patients should follow the advice of the doctor regarding its use.

Can I take Urovin (100mg) while breastfeeding/lactation?

Moderately safe: No studies have been conducted in breastfeeding women, however there is possibility of ill effect to the breastfed infants; or studies conducted in breastfeeding women show minimal non-threatening side effects to the infants. Drugs should be given only if the potential benefit justifies the potential risk to the infant. Patients should follow the advice of the doctor regarding its use.

Can I take Urovin (100mg) with alcohol?

No studies found