Mephenesin

INFORMATION

TYPICAL USAGE

Muscle spasm (acute).

SIDE EFFECTS

Lassitude, drowsiness, weakness, loss of appetite.

DRUG INTERACTION

Additive CNS effects with CNS depressants e.g. barbiturates, alcohol, opioids.

MECHANISM OF ACTION

Mephenesin acts by decreasing the muscle tone without reducing voluntary power.It selectively inhibits polysynaptic reflexes in CNS.

AVAILABLE MEDICINE

INTERACTIONS

IMPACT ON PREGNANCY

Studies in animals have shown risk to fetus, however there are no sufficient studies in humans. This drug may be used in pregnant women if benefit outweighs the risk. Patients should follow the advice of the doctor regarding its use.

IMPACT DURING LACTATION

Possibly unsafe: Evidence from studies in breastfeeding women show that there is a definite risk of side effects to the breastfed infants. However, use of the drug in breastfeeding women is acceptable in spite of the risk to the infants, if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective. Patients should follow the advice of the doctor regarding its use.

MEDICINE & ALCOHOL USE

No studies found